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NCT07419841 · ClinicalTrials.gov registry record · Phase 1
A Phase 1 Study of the Safety and Tolerability of CTX-10726
A Phase 1 study, sponsored by Compass Therapeutics.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 70
- Enrollment target
NCT07419841: Recruiting Phase 1 study, sponsored by Compass Therapeutics.
NCT07419841 is a Phase 1 study that is actively recruiting participants, run by Compass Therapeutics. The registered enrollment target is 70 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07419841, a Phase 1 study, is actively recruiting participants, sponsored by Compass Therapeutics.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 70 participants
- Enrollment target
Study Summary
This is a Phase 1, open-label, first-in-human study of CTX-10726 monotherapy in patients with metastatic or locally advanced malignancies. The study will be conducted in 2 Cohorts: Cohort 1 Dose Escalation and Cohort 2 Dose Expansion.
Primary Outcome
Incidence of dose limiting toxicities (DLTs), treatment-emergent adverse events (TEAEs), and/or changes in clinical laboratory abnormalities.
Interventions
- DRUG CTX-10726
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2026-05-28 |
| Est. Completion | 2028-11-01 |
| Phase | Phase 1 |
What NCT07419841 shows while recruiting
NCT07419841 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% higher).
The record links to 0 conditions, and to 1 intervention - of which CTX-10726 is the first listed.
NCT07419841 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07419841 about?
NCT07419841 is a clinical study titled "A Phase 1 Study of the Safety and Tolerability of CTX-10726". This is a Phase 1, open-label, first-in-human study of CTX-10726 monotherapy in patients with metastatic or locally advanced malignancies. The study will be conducted in 2 Cohorts: Cohort 1 Dose Escalation and Cohort 2 Dose Expansion.
What is the current status of trial NCT07419841?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 70 participants. The study started on 2026-05-28. Estimated completion is 2028-11-01.
What interventions are being tested in trial NCT07419841?
The interventions under investigation include: CTX-10726 (DRUG).
Who is sponsoring clinical trial NCT07419841?
This trial is sponsored by Compass Therapeutics, which has 5 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07419841's enrollment target sits among peer trials
70 749th of 2000 higher than 1,227 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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