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NCT07418112 · ClinicalTrials.gov registry record · Phase 4
Comparing the Efficacy and Safety of Holmium Laser Lithotripsy Versus Electrohydraulic Lithotripsy for the Treatment of Difficult Choledocholithiasis and Pancreatic Duct Stones
A Phase 4 study of Choledocholithiasis and Pancreatic Duct Stone, sponsored by Rush University Medical Center.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT07418112: Recruiting Phase 4 study of Choledocholithiasis and Pancreatic Duct Stone, sponsored by Rush University Medical Center.
NCT07418112 is a Phase 4 study of Choledocholithiasis and Pancreatic Duct Stone that is actively recruiting participants, run by Rush University Medical Center. The registered enrollment target is 40 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07418112, a Phase 4 study of Choledocholithiasis and Pancreatic Duct Stone, is actively recruiting participants, sponsored by Rush University Medical Center.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to learn if a low-power holmium laser works to treat large and/or difficult bile duct or pancreatic duct stones in adults. It will also learn about the safety of the low-wattage holmium laser. The main questions it aims to answer are: Is the low-power holmium laser effective at treating large and/or difficult bile duct or pancreatic duct stones? Is the low-power holmium laser effective safe to use in adults? How does the low-power holmium laser compare to electrohydraulic lithotripsy for the management of large and/or difficult bile duct or pancreatic duct stones. Participants will: Undergo ERCP procedure and their bile duct or pancreatic duct stone will either be broken up with the low-power holmium laser lithotripsy device or the electrohydraulic lithotripsy lithotripsy device. Answer a call 30 days after the procedure to document symptoms and/or any side effects.
Primary Outcome
Complete stone clearance is defined as the lithotripsy and clearance of ductal stone fragments as confirmed on cholangiogram or pancreaticogram at the end of the index/first procedure of the study.
Conditions Studied
Interventions
- DEVICE Laser lithotripsy with low-wattage holmium laser
- DEVICE Electrohydraulic lithotripsy
Study Locations (1)
Illinois
- Rush University Medical Center - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2026-01-15 |
| Est. Completion | 2027-12 |
| Phase | Phase 4 |
What NCT07418112 shows while recruiting
NCT07418112 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower).
The record links to 2 conditions, with Choledocholithiasis appearing as the primary indexed condition, and to 2 interventions - of which Laser lithotripsy with low-wattage holmium laser is the first listed.
NCT07418112 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT07418112 about?
NCT07418112 is a clinical study titled "Comparing the Efficacy and Safety of Holmium Laser Lithotripsy Versus Electrohydraulic Lithotripsy for the Treatment of Difficult Choledocholithiasis and Pancreatic Duct Stones". The goal of this clinical trial is to learn if a low-power holmium laser works to treat large and/or difficult bile duct or pancreatic duct stones in adults. It will also learn about the safety of the low-wattage holmium laser. The main questions it aims to answer are: Is the low-power holmium lase...
What is the current status of trial NCT07418112?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 40 participants. The study started on 2026-01-15. Estimated completion is 2027-12.
What conditions does trial NCT07418112 study?
This clinical trial studies the following conditions: Choledocholithiasis, Pancreatic Duct Stone.
What interventions are being tested in trial NCT07418112?
The interventions under investigation include: Laser lithotripsy with low-wattage holmium laser (DEVICE), Electrohydraulic lithotripsy (DEVICE).
Who is sponsoring clinical trial NCT07418112?
This trial is sponsored by Rush University Medical Center, which has 320 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07418112 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT07418112's enrollment target sits among peer trials
40 1397th of 2000 higher than 534 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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