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NCT07405645 · ClinicalTrials.gov registry record · NA

Stereotactic MRI-guided Focused Ultrasound Mesencephalotomy

A NA study of Cancer Pain and Head Neck Cancer, sponsored by University of Virginia.

Recruiting
Registry status
NA
Development phase
20
Enrollment target
6
Study locations

NCT07405645 is a NA study of Cancer Pain and Head Neck Cancer that is actively recruiting participants, run by University of Virginia. The registered enrollment target is 20 participants, below the 161-participant average among 15 other Cancer Pain trials with a reported enrollment target (88% lower). The trial reports 6 study locations across 5 states.

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The verdict

NCT07405645, a NA study of Cancer Pain and Head Neck Cancer, is actively recruiting participants, sponsored by University of Virginia.

RECRUITING
Registry status
NA
Development phase
20 participants
Enrollment target
6
Study locations

Study Summary

This phase 1 multi-site study investigates the safety and initial effectiveness of focused ultrasound lesioning of the contralateral mesencephalon for severe, opioid-resistant pain associated with head and neck cancer and brachial cancer.

Conditions Studied

Cancer Pain Head Neck Cancer Squamous Cell Cancer of Head and Neck (SCCHN)

Interventions

  • DEVICE ExAblate Neuro

Study Locations (6)

Texas

  • The University of Texas Southwestern Medical Center - Dallas
  • Baylor College of Medicine - Houston

Massachusetts

  • Brigham and Women's Hospital - Boston

New York

  • Weill Cornell Medicine - New York

Oregon

  • Oregon Health and Science University - Portland

Virginia

  • University of Virginia - Charlottesville

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2026-02-15
Est. Completion 2029-12-31
Phase NA

Sponsor

University of Virginia

449 total trials

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What the Registry Record Tells You About NCT07405645

The ClinicalTrials.gov registry entry for NCT07405645 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 161-participant average among 15 other Cancer Pain trials with a reported enrollment target (88% lower). The listed sponsor is University of Virginia, which has 449 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Cancer Pain appearing as the primary indexed condition, and to 1 intervention - of which ExAblate Neuro is the first listed.

NCT07405645 reports 6 study locations spanning 5 distinct geographic areas - top geographies include Texas, Massachusetts, New York.

Frequently Asked Questions

What is clinical trial NCT07405645 about?

NCT07405645 is a clinical study titled "Stereotactic MRI-guided Focused Ultrasound Mesencephalotomy". This phase 1 multi-site study investigates the safety and initial effectiveness of focused ultrasound lesioning of the contralateral mesencephalon for severe, opioid-resistant pain associated with head and neck cancer and brachial cancer.

What is the current status of trial NCT07405645?

This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2026-02-15. Estimated completion is 2029-12-31.

What conditions does trial NCT07405645 study?

This clinical trial studies the following conditions: Cancer Pain, Head Neck Cancer, Squamous Cell Cancer of Head and Neck (SCCHN).

What interventions are being tested in trial NCT07405645?

The interventions under investigation include: ExAblate Neuro (DEVICE).

Who is sponsoring clinical trial NCT07405645?

This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07405645 being conducted?

This trial has 6 study locations across Massachusetts, New York, Oregon, Texas, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.