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NCT07392879 · ClinicalTrials.gov registry record · NA

Bringing the Outdoors In: Virtual Nature Walks for Depression in Multiple Sclerosis (MS) Patients

A NA study of Depression and Progressive Multiple Sclerosis, sponsored by University of Michigan.

Recruiting
Registry status
NA
Development phase
40
Enrollment target
1
Study location

NCT07392879: Recruiting NA study of Depression and Progressive Multiple Sclerosis, sponsored by University of Michigan.

NCT07392879 is a NA study of Depression and Progressive Multiple Sclerosis that is actively recruiting participants, run by University of Michigan. The registered enrollment target is 40 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07392879, a NA study of Depression and Progressive Multiple Sclerosis, is actively recruiting participants, sponsored by University of Michigan.

RECRUITING
Registry status
NA
Development phase
40 participants
Enrollment target
1
Study location

Study Summary

This trial explores the use of immersive virtual reality (VR) nature-based experiences as a supplementary treatment for depression in individuals with progressive multiple sclerosis (MS). This study will evaluate the feasibility and efficacy of at-home VR deployment using the Apple Vision Pro, an advanced device that offers enhanced resolution, immersion, and usability compared to earlier VR systems. The study hypotheses include: * The integration of VR nature-based experiences with standard care will be feasible, acceptable, and will result in greater reductions in depressive symptoms compared to standard care or VR-only interventions. * The integration of VR nature-based experiences with standard care will result in greater reductions in stress and anxiety, better sleep, less insomnia, and improved fatigue compared to standard care alone or VR-only interventions.

Primary Outcome

This is an 8-item evaluating various aspects of depression, including negative mood, anhedonia, feelings of worthlessness, and cognitive impairments. Each item is rated on a 5-point Likert scale ranging from never (1) - always (5). Scores range from 8-40 with a higher score indicating greater symptom severity.

Interventions

  • OTHER Standard care
  • DEVICE Virtual Reality

Study Locations (1)

Michigan

  • University of Michigan - Ann Arbor

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2025-12-15
Est. Completion 2027-04
Phase NA
University of Michigan

1,327 total trials

What NCT07392879 shows while recruiting

NCT07392879 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 786-participant average among 679 other Depression trials with a reported enrollment target (95% lower).

The record links to 2 conditions, with Depression appearing as the primary indexed condition, and to 2 interventions - of which Standard care is the first listed.

NCT07392879 reports a single indexed study location in Michigan.

Frequently Asked Questions

What is clinical trial NCT07392879 about?

NCT07392879 is a clinical study titled "Bringing the Outdoors In: Virtual Nature Walks for Depression in Multiple Sclerosis (MS) Patients". This trial explores the use of immersive virtual reality (VR) nature-based experiences as a supplementary treatment for depression in individuals with progressive multiple sclerosis (MS). This study will evaluate the feasibility and efficacy of at-home VR deployment using the Apple Vision Pro, an ad...

What is the current status of trial NCT07392879?

This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2025-12-15. Estimated completion is 2027-04.

What conditions does trial NCT07392879 study?

This clinical trial studies the following conditions: Depression, Progressive Multiple Sclerosis.

What interventions are being tested in trial NCT07392879?

The interventions under investigation include: Standard care (OTHER), Virtual Reality (DEVICE).

Who is sponsoring clinical trial NCT07392879?

This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07392879 being conducted?

This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Depression

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT07392879's enrollment target sits among peer trials

40 509th of 679 higher than 151 of 679 other Depression trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07392879, the US trial registry maintained by the National Library of Medicine. NCT07392879 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.