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NCT07391592 · ClinicalTrials.gov registry record

Post Market Clinical Follow-Up Study for EVOLUTION® NitrX™ Keeled Tibia and EVOLUTION® NitrX™ CS/CR Femur With Cruciate Sacrificing Insert

A clinical trial of Avascular Necrosis and Joint Diseases, sponsored by MicroPort Orthopedics.

Active
Registry status
100
Enrollment target
1
Study location

NCT07391592 is a study of Avascular Necrosis and Joint Diseases that is active but no longer recruiting, run by MicroPort Orthopedics. The registered enrollment target is 100 participants, below the 291-participant average among 24 other Avascular Necrosis trials with a reported enrollment target (66% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07391592, a study of Avascular Necrosis and Joint Diseases, is active but no longer recruiting, sponsored by MicroPort Orthopedics.

ACTIVE NOT RECRUITING
Registry status
100 participants
Enrollment target
1
Study location

Study Summary

MicroPort Orthopedics Inc. (MPO) plans to market the EVOLUTION® NitrX™ Non-Porous Keeled Tibia and EVOLUTION® NitrX™ CS/CR Non-Porous Femur with the EVOLUTION® Cruciate Sacrificing (CS) Tibial Insert globally, including in the European Union (EU). MPO is conducting this post market clinical follow-up (PMCF) study to evaluate the safety and effectiveness of the EVOLUTION® NitrX™ Non-Porous Keeled Tibia and EVOLUTION® NitrX™ CS/CR Non-Porous Femur. These components are used along with the EVOLUTION® Cruciate Sacrificing (CS) Tibial Insert components that is marketed in the European Union (EU). This type of data collection is required by regulatory authorities for all TKA devices that do not have medium to long-term clinical evidence available.

Interventions

  • DEVICE EVOLUTION® NitrX™

Study Locations (1)

California

  • Sah Orthopaedic Associates - Fremont

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2025-08-18
Est. Completion 2032-12-31

Sponsor

MicroPort Orthopedics

7 total trials

What the Registry Record Tells You About NCT07391592

The ClinicalTrials.gov registry entry for NCT07391592 describes a study currently listed as active not recruiting, categorized as an unspecified phase. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 291-participant average among 24 other Avascular Necrosis trials with a reported enrollment target (66% lower). The listed sponsor is MicroPort Orthopedics, which has 7 total studies on file at ClinicalTrials.gov.

The record links to 5 conditions, with Avascular Necrosis appearing as the primary indexed condition, and to 1 intervention - of which EVOLUTION® NitrX™ is the first listed.

NCT07391592 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT07391592 about?

NCT07391592 is a clinical study titled "Post Market Clinical Follow-Up Study for EVOLUTION® NitrX™ Keeled Tibia and EVOLUTION® NitrX™ CS/CR Femur With Cruciate Sacrificing Insert". MicroPort Orthopedics Inc. (MPO) plans to market the EVOLUTION® NitrX™ Non-Porous Keeled Tibia and EVOLUTION® NitrX™ CS/CR Non-Porous Femur with the EVOLUTION® Cruciate Sacrificing (CS) Tibial Insert globally, including in the European Union (EU). MPO is conducting this post market clinical follow-u...

What is the current status of trial NCT07391592?

This trial is currently active not recruiting. The enrollment target is 100 participants. The study started on 2025-08-18. Estimated completion is 2032-12-31.

What conditions does trial NCT07391592 study?

This clinical trial studies the following conditions: Avascular Necrosis, Joint Diseases, Arthritis Knee, Rheumatoid Arthritis of Knee, Osteoarthitis.

What interventions are being tested in trial NCT07391592?

The interventions under investigation include: EVOLUTION® NitrX™ (DEVICE).

Who is sponsoring clinical trial NCT07391592?

This trial is sponsored by MicroPort Orthopedics, which has 7 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07391592 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.