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NCT07382739 · ClinicalTrials.gov registry record · Phase 2

A Phase 2 Study of Radiotherapy-induced Immune Priming to Enhance Elranatamab (Elra) in Relapsed Refractory Multiple Myeloma (RRMM) With Extramedullary Disease (EMD) and Paramedullary Disease (PMD) "PRIME-EMD-PMD"

A Phase 2 study, sponsored by M.D. Anderson Cancer Center.

Recruiting
Registry status
Phase 2
Development phase
34
Enrollment target

NCT07382739: Recruiting Phase 2 study, sponsored by M.D. Anderson Cancer Center.

NCT07382739 is a Phase 2 study that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 34 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (74% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT07382739, a Phase 2 study, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.

RECRUITING
Registry status
Phase 2
Development phase
34 participants
Enrollment target

Study Summary

To learn if low doses of radiation therapy can help the drug elranatamab enhance the killing effect of the cancer cells.

Primary Outcome

Incidence of Adverse Events, Graded According to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) Version (v) 5.0

Interventions

  • DRUG Elranatamab

Trial Details

FieldValue
Enrollment Target 34 participants
Start Date 2026-03-31
Est. Completion 2030-12-31
Phase Phase 2
M.D. Anderson Cancer Center

2,692 total trials

What NCT07382739 shows while recruiting

NCT07382739 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 34 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (74% lower).

The record links to 0 conditions, and to 1 intervention - of which Elranatamab is the first listed.

NCT07382739 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07382739 about?

NCT07382739 is a clinical study titled "A Phase 2 Study of Radiotherapy-induced Immune Priming to Enhance Elranatamab (Elra) in Relapsed Refractory Multiple Myeloma (RRMM) With Extramedullary Disease (EMD) and Paramedullary Disease (PMD) "PRIME-EMD-PMD"". To learn if low doses of radiation therapy can help the drug elranatamab enhance the killing effect of the cancer cells.

What is the current status of trial NCT07382739?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 34 participants. The study started on 2026-03-31. Estimated completion is 2030-12-31.

What interventions are being tested in trial NCT07382739?

The interventions under investigation include: Elranatamab (DRUG).

Who is sponsoring clinical trial NCT07382739?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07382739's enrollment target sits among peer trials

34 1539th of 2000 higher than 448 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07382739, the US trial registry maintained by the National Library of Medicine. NCT07382739 (small enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.