Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07380906 · ClinicalTrials.gov registry record
Prospective Registry For Genicular Artery Embolization At The Joint & Vascular Institute
A clinical trial of Knee Osteoarthristis, sponsored by Joint & Vascular Institute.
- Recruiting
- Registry status
- 1,200
- Enrollment target
- 1
- Study location
NCT07380906: Recruiting study of Knee Osteoarthristis, sponsored by Joint & Vascular Institute.
NCT07380906 is a study of Knee Osteoarthristis that is actively recruiting participants, run by Joint & Vascular Institute. The registered enrollment target is 1,200 participants, above the 114-participant average among 3 other Knee Osteoarthristis trials with a reported enrollment target (953% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07380906, a study of Knee Osteoarthristis, is actively recruiting participants, sponsored by Joint & Vascular Institute.
- RECRUITING
- Registry status
- 1,200 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this observational study (prospective registry) is to collect long-term real-world data on the effectiveness and safety of genicular artery embolization (GAE) for knee osteoarthritis in adults aged 18 years or older with symptomatic KOA that has not responded to medical therapy. The main questions it aims to answer are: 1. Does GAE lead to sustained improvement in pain (WOMAC, VAS) and quality-of-life scores over 12-36 months? 2. What patient or procedural factors are associated with better outcomes after GAE? Participants will: * Undergo GAE as part of their routine clinical care. * Complete clinical follow-up assessments at 1, 3, 6, 12, 18, 24, and 36 months after treatment, including symptom and quality-of-life questionnaires. * Have safety outcomes tracked according to Society of Interventional Radiology guidelines. There is no comparison group; results will be analyzed to identify predictors of success and inform best practices for patient selection and treatment.
Primary Outcome
The investigators will describe differences in pain response with Genicular Artery Embolization (GAE) compared to a sham procedure when treating medically refractory mild to moderate Knee Osteoarthritis (KOA) at 12 months as measured by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain subscale score. A higher score index a higher pain level while a lower score indicates lower pain levels. The score range is 0 to 96.
Conditions Studied
Interventions
- PROCEDURE Genicular Artery Embolization
Study Locations (1)
Illinois
- Joint and Vascular Institute - Libertyville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,200 participants |
| Start Date | 2025-07-16 |
| Est. Completion | 2030-07 |
What NCT07380906 shows while recruiting
NCT07380906 is an observational study that tracks outcomes without assigning an intervention. Its 1,200 participants enrollment target places it among the larger protocols in the corpus, above the 114-participant average among 3 other Knee Osteoarthristis trials with a reported enrollment target (953% higher).
The record links to 1 condition, with Knee Osteoarthristis appearing as the primary indexed condition, and to 1 intervention - of which Genicular Artery Embolization is the first listed.
NCT07380906 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT07380906 about?
NCT07380906 is a clinical study titled "Prospective Registry For Genicular Artery Embolization At The Joint & Vascular Institute". The goal of this observational study (prospective registry) is to collect long-term real-world data on the effectiveness and safety of genicular artery embolization (GAE) for knee osteoarthritis in adults aged 18 years or older with symptomatic KOA that has not responded to medical therapy. The mai...
What is the current status of trial NCT07380906?
This trial is currently recruiting. The enrollment target is 1,200 participants. The study started on 2025-07-16. Estimated completion is 2030-07.
What conditions does trial NCT07380906 study?
This clinical trial studies the following conditions: Knee Osteoarthristis.
What interventions are being tested in trial NCT07380906?
The interventions under investigation include: Genicular Artery Embolization (PROCEDURE).
Who is sponsoring clinical trial NCT07380906?
This trial is sponsored by Joint & Vascular Institute, which has 4 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07380906 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Knee Osteoarthristis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00001987 · 1,200 participants
Genetic Studies of Insulin and Diabetes
- NCT00477100 · 1,200 participants
Biospecimen and Medical Data Collection and Tumor Biopsy in Creating Research Tissue Registry in Patients With Inflammatory or Invasive Breast Cancer
- NCT01209000 · 1,200 participants
Nephrotic Syndrome Study Network
- NCT01944332 · 1,200 participants · NA
Gamete Treatment to Correct Fertilization Failure
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI