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NCT07354477 · ClinicalTrials.gov registry record · Phase 2

Single-site Pilot Study Evaluating the Effect of QLS-111 Ophthalmic Solution on Posterior Perfusion and Vessel Dilation

A Phase 2 study of Open Angle Glaucoma (OAG) and Non-proliferative Diabetic Retinopathy (NPDR), sponsored by Qlaris Bio.

Recruiting
Registry status
Phase 2
Development phase
14
Enrollment target
1
Study location

NCT07354477 is a Phase 2 study of Open Angle Glaucoma (OAG) and Non-proliferative Diabetic Retinopathy (NPDR) that is actively recruiting participants, run by Qlaris Bio. The registered enrollment target is 14 participants, below the 66-participant average among 5 other Open Angle Glaucoma (OAG) trials with a reported enrollment target (79% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07354477, a Phase 2 study of Open Angle Glaucoma (OAG) and Non-proliferative Diabetic Retinopathy (NPDR), is actively recruiting participants, sponsored by Qlaris Bio.

RECRUITING
Registry status
Phase 2
Development phase
14 participants
Enrollment target
1
Study location

Study Summary

Pilot, single-site, prospective study of QLS-111 0.015 % in subjects with NPDR, OAG or NTG

Interventions

  • DRUG QLS-111 Ophthalmic Solution (0.015%)
  • DRUG QLS-111 Ophthalmic Solution (0.075%)

Study Locations (1)

California

  • Stanford University, Dept. of Ophthalmology - Palo Alto

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2026-02-20
Est. Completion 2026-06
Phase Phase 2

Sponsor

Qlaris Bio

8 total trials

What the Registry Record Tells You About NCT07354477

The ClinicalTrials.gov registry entry for NCT07354477 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 14 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 66-participant average among 5 other Open Angle Glaucoma (OAG) trials with a reported enrollment target (79% lower). The listed sponsor is Qlaris Bio, which has 8 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Open Angle Glaucoma (OAG) appearing as the primary indexed condition, and to 2 interventions - of which QLS-111 Ophthalmic Solution (0.015%) is the first listed.

NCT07354477 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT07354477 about?

NCT07354477 is a clinical study titled "Single-site Pilot Study Evaluating the Effect of QLS-111 Ophthalmic Solution on Posterior Perfusion and Vessel Dilation". Pilot, single-site, prospective study of QLS-111 0.015 % in subjects with NPDR, OAG or NTG

What is the current status of trial NCT07354477?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 14 participants. The study started on 2026-02-20. Estimated completion is 2026-06.

What conditions does trial NCT07354477 study?

This clinical trial studies the following conditions: Open Angle Glaucoma (OAG), Non-proliferative Diabetic Retinopathy (NPDR), Normal Tension Glaucoma (NTG).

What interventions are being tested in trial NCT07354477?

The interventions under investigation include: QLS-111 Ophthalmic Solution (0.015%) (DRUG), QLS-111 Ophthalmic Solution (0.075%) (DRUG).

Who is sponsoring clinical trial NCT07354477?

This trial is sponsored by Qlaris Bio, which has 8 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07354477 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Open Angle Glaucoma (OAG)

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.