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NCT07331077 · ClinicalTrials.gov registry record · NA

A Physical Activity Program Compared to Health Education for Improving Memory and Attention in Hispanic Women With Newly-Diagnosed Stage I-IIIa Breast Cancer, MAMA Trial

A NA study, sponsored by Mayo Clinic.

Not yet
Registry status
NA
Development phase
10
Enrollment target

NCT07331077: Clinical Trial NA study, sponsored by Mayo Clinic.

NCT07331077 is a NA study that has not yet begun recruiting, run by Mayo Clinic. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT07331077, a NA study, has not yet begun recruiting, sponsored by Mayo Clinic.

NOT YET RECRUITING
Registry status
NA
Development phase
10 participants
Enrollment target

Study Summary

This clinical trial compares a physical activity program to a health education program for improving memory and attention in Hispanic women who are 50 years of age or older and are newly-diagnosed with stage I-IIIa breast cancer. Compared to non-Hispanic White breast cancer survivors (BCS), Hispanic BCS report greater depressive symptoms, emotional distress, anxiety, fear of recurrence, pain, fatigue, and financial toxicity, in addition to more cancer-related psychosocial needs and lower quality of life and social well-being. Cancer-associated cognitive decline (CACD) is a related symptom that has gained increasing attention in clinical research. Based on disparities in other outcomes, it is likely that Hispanic BCS also experience greater CACD than non-Hispanic White BCS, but interventions targeting CACD in Hispanic BCS are non-existent and critically needed. The benefits of aerobic exercise among BCS are well documented and include improvement in health outcomes that are associated with cognitive function including fatigue, anxiety, depression, and sleep. A physical activity program that includes aerobic exercise may be more effective than simple health education for improving cognitive functions like memory and attention in Hispanic women who are 50 years of age or older and are newly-diagnosed with stage I-IIIa breast cancer.

Primary Outcome

Change in interference score on Stroop task, with positive values indicating greater inhibitory control

Interventions

  • OTHER Electronic Health Record Review
  • PROCEDURE Accelerometry
  • OTHER Aerobic Exercise
  • PROCEDURE Functional Magnetic Resonance Imaging
  • OTHER Gait Assessment Test

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2026-10-01
Est. Completion 2027-11-30
Phase NA
Mayo Clinic

2,844 total trials

What is known before NCT07331077 opens enrollment

NCT07331077 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 5 interventions - of which Electronic Health Record Review is the first listed.

NCT07331077 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07331077 about?

NCT07331077 is a clinical study titled "A Physical Activity Program Compared to Health Education for Improving Memory and Attention in Hispanic Women With Newly-Diagnosed Stage I-IIIa Breast Cancer, MAMA Trial". This clinical trial compares a physical activity program to a health education program for improving memory and attention in Hispanic women who are 50 years of age or older and are newly-diagnosed with stage I-IIIa breast cancer. Compared to non-Hispanic White breast cancer survivors (BCS), Hispanic...

What is the current status of trial NCT07331077?

This trial is currently not yet recruiting. It is a NA study. The enrollment target is 10 participants. The study started on 2026-10-01. Estimated completion is 2027-11-30.

What interventions are being tested in trial NCT07331077?

The interventions under investigation include: Electronic Health Record Review (OTHER), Accelerometry (PROCEDURE), Aerobic Exercise (OTHER), Functional Magnetic Resonance Imaging (PROCEDURE), Gait Assessment Test (OTHER).

Who is sponsoring clinical trial NCT07331077?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07331077's enrollment target sits among peer trials

10 1927th of 2000 higher than 26 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07331077, the US trial registry maintained by the National Library of Medicine. NCT07331077 (small enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.