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NCT07311993 · ClinicalTrials.gov registry record · Phase 1
Phase 1 Study of CLR 125 in Triple Negative Breast Cancer
A Phase 1 study of Breast Cancer, sponsored by Cellectar Biosciences.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 60
- Enrollment target
- 2
- Study locations
NCT07311993: Recruiting Phase 1 study of Breast Cancer, sponsored by Cellectar Biosciences.
NCT07311993 is a Phase 1 study of Breast Cancer that is actively recruiting participants, run by Cellectar Biosciences. The registered enrollment target is 60 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (98% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07311993, a Phase 1 study of Breast Cancer, is actively recruiting participants, sponsored by Cellectar Biosciences.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 60 participants
- Enrollment target
- 2
- Study locations
Study Summary
The goal of this clinical trial is to evaluate the safety and efficacy of 3 different dose levels of CLR 125 in patients with advanced triple negative breast cancer. The main questions the study aims to answer are: * What dose and regimen should be used in future trials of CLR 125 in patients with advanced triple negative breast cancer. * What side effects do participants have when taking CLR 125. Participants will: * Have CLR 125 administered via infusion 4 times each cycle; repeated every 8 weeks. * Visit the clinic once every 3 weeks for checkups and testing. * Report any side effects or new medications. Some participants may also receive one dose of CLR 131 to evaluate the amount of radiation delivered to various organs and to the tumor. These participants will: * Have 4 scans completed over 2 weeks * Have blood drawn 6 times over 2 weeks.
Primary Outcome
Identify the recommended Phase 2 dose and regimen of CLR 125 in advanced TNBC patients
Conditions Studied
Interventions
- DRUG Iopofosine I 131
- DRUG CLR 125
Study Locations (2)
Florida
- Mayo Clinic Florida - Jacksonville
Maryland
- United Theranostics - Glen Burnie
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2025-12-05 |
| Est. Completion | 2029-07 |
| Phase | Phase 1 |
What NCT07311993 shows while recruiting
NCT07311993 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 2 interventions - of which Iopofosine I 131 is the first listed.
NCT07311993 reports a single indexed study location in Florida, Maryland.
Frequently Asked Questions
What is clinical trial NCT07311993 about?
NCT07311993 is a clinical study titled "Phase 1 Study of CLR 125 in Triple Negative Breast Cancer". The goal of this clinical trial is to evaluate the safety and efficacy of 3 different dose levels of CLR 125 in patients with advanced triple negative breast cancer. The main questions the study aims to answer are: * What dose and regimen should be used in future trials of CLR 125 in patients with ...
What is the current status of trial NCT07311993?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 60 participants. The study started on 2025-12-05. Estimated completion is 2029-07.
What conditions does trial NCT07311993 study?
This clinical trial studies the following conditions: Breast Cancer.
What interventions are being tested in trial NCT07311993?
The interventions under investigation include: Iopofosine I 131 (DRUG), CLR 125 (DRUG).
Who is sponsoring clinical trial NCT07311993?
This trial is sponsored by Cellectar Biosciences, which has 10 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07311993 being conducted?
This trial has 2 study locations across Florida, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Breast Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07311993's enrollment target sits among peer trials
60 736th of 1224 higher than 468 of 1,224 other Breast Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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