Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING Phase 2

Study of ENV-294 in Adults With Moderate-to-Severe Atopic Dermatitis

NCT07298395 · View on ClinicalTrials.gov ↗

Study Summary

The goal of this clinical trial is to learn about the safety and effectiveness of ENV-294 in adults with moderate to severe atopic dermatitis. The main questions it will answer are: * Is there an impact on the severity and area of atopic dermatitis when participants take ENV-294 * What medical problems do participants have when taking ENV-294 Researchers will review the atopic dermatitis present at the beginning of the study against the atopic dermatitis present at the end of the study. Participants will: * Take drug ENV-294 or a placebo once every day for 12 weeks * Visit the clinic every 2 to 4 weeks for checkups and tests * Keep a diary of their symptoms and when they took their study drug ENV-294 * Return to the clinic for the final study visit at approximately week 16

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG ENV-294

Study Locations (12)

Texas

  • Arlington Research Center — Arlington
  • Center for Clinical Studies — Houston
  • Texas Dermatology and Laser Specialists — San Antonio

California

  • Center for Dermatology Clinical Research — Fremont
  • TCR Medical Corporation — San Diego

Indiana

  • Southern Indiana Clinical Trials — New Albany
  • Options Research Group — West Lafayette

Alabama

  • Cahaba & Skin Health Center — Birmingham

Arkansas

  • Burke Pharmaceutical Research — Hot Springs

Michigan

  • Michigan Center for Skin Care Research — Clinton Township

Pennsylvania

  • Best Skin Research — Camp Hill

Virginia

  • Virginia Dermatology & Skin Cancer Center — Norfolk

Trial Details

FieldValue
Enrollment Target 64 participants
Start Date 2025-12-22
Est. Completion 2026-12
Phase Phase 2

Sponsor

Enveda Therapeutics

3 total trials

Interested in This Trial?

Always speak with your doctor before enrolling in a clinical trial.

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07298395

The ClinicalTrials.gov registry entry for NCT07298395 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 64 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Enveda Therapeutics, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Atopic Dermatitis (AD) appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07298395 reports 12 study locations spanning 8 distinct geographic areas — top geographies include Texas, California, Indiana. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07298395 about?

NCT07298395 is a clinical study titled "Study of ENV-294 in Adults With Moderate-to-Severe Atopic Dermatitis". The goal of this clinical trial is to learn about the safety and effectiveness of ENV-294 in adults with moderate to severe atopic dermatitis. The main questions it will answer are: * Is there an impact on the severity and area of atopic dermatitis when participants take ENV-294 * What medical pro...

What is the current status of trial NCT07298395?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 64 participants. The study started on 2025-12-22. Estimated completion is 2026-12.

What conditions does trial NCT07298395 study?

This clinical trial studies the following conditions: Atopic Dermatitis (AD). These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07298395?

The interventions under investigation include: Placebo (DRUG), ENV-294 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07298395?

This trial is sponsored by Enveda Therapeutics, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07298395 being conducted?

This trial has 12 study locations across Alabama, Arkansas, California, Indiana, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial