Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT07294924 · ClinicalTrials.gov registry record

Prediction of REsponse to Depression Interventions (Accelerated rTMS) Using Clinical and TD-fNIRS Measurements

A clinical trial of Major Depressive Disorder (MDD) and fNIRS, sponsored by Kernel.

Recruiting
Registry status
100
Enrollment target
2
Study locations

NCT07294924 is a study of Major Depressive Disorder (MDD) and fNIRS that is actively recruiting participants, run by Kernel. The registered enrollment target is 100 participants, below the 154-participant average among 22 other Major Depressive Disorder (MDD) trials with a reported enrollment target (35% lower). The trial reports 2 study locations across 1 state.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT07294924, a study of Major Depressive Disorder (MDD) and fNIRS, is actively recruiting participants, sponsored by Kernel.

RECRUITING
Registry status
100 participants
Enrollment target
2
Study locations

Study Summary

This observational, longitudinal, multi-cohort study aims to evaluate functional brain activity in adults undergoing treatment for Major Depressive Disorder (MDD) at participating clinical sites. A separate cohort of healthy adults will be enrolled as a control group. All data collected in this study are for research purposes only and will not influence clinical decision-making or treatment plans. This study will use TD-fNIRS to measure hemodynamic brain responses at rest and/or during tasks in patients receiving accelerated transcranial magnetic stimulation (TMS). Imaging will occur at multiple timepoints (pre-treatment, post-treatment, and follow-ups). Healthy control participants will complete similar measurements at one visit, with the option for a follow-up visit. The primary objectives are to assess feasibility, characterize brain activity patterns, and explore potential biomarkers associated with treatment response.

Conditions Studied

Major Depressive Disorder (MDD) fNIRS

Interventions

  • OTHER fNIRS measurement

Study Locations (2)

California

  • Kernel - Los Angeles
  • Acacia Clinics - Sunnyvale

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2025-12-15
Est. Completion 2026-12-15

Sponsor

Kernel

2 total trials

Interested in This Trial?

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07294924

The ClinicalTrials.gov registry entry for NCT07294924 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 154-participant average among 22 other Major Depressive Disorder (MDD) trials with a reported enrollment target (35% lower). The listed sponsor is Kernel, which has 2 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Major Depressive Disorder (MDD) appearing as the primary indexed condition, and to 1 intervention - of which fNIRS measurement is the first listed.

NCT07294924 reports 2 study locations spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT07294924 about?

NCT07294924 is a clinical study titled "Prediction of REsponse to Depression Interventions (Accelerated rTMS) Using Clinical and TD-fNIRS Measurements". This observational, longitudinal, multi-cohort study aims to evaluate functional brain activity in adults undergoing treatment for Major Depressive Disorder (MDD) at participating clinical sites. A separate cohort of healthy adults will be enrolled as a control group. All data collected in this stud...

What is the current status of trial NCT07294924?

This trial is currently recruiting. The enrollment target is 100 participants. The study started on 2025-12-15. Estimated completion is 2026-12-15.

What conditions does trial NCT07294924 study?

This clinical trial studies the following conditions: Major Depressive Disorder (MDD), fNIRS.

What interventions are being tested in trial NCT07294924?

The interventions under investigation include: fNIRS measurement (OTHER).

Who is sponsoring clinical trial NCT07294924?

This trial is sponsored by Kernel, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07294924 being conducted?

This trial has 2 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Major Depressive Disorder (MDD)

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Explore more on PlainTrial

Major Depressive Disorder (MDD)

All registered trials for this condition

fNIRS

All registered trials for this condition

California

All trials with a study site in California

Recruiting now

Find trials open to new participants near you

Rankings

Top sponsors, conditions, and phases

Read our methodology - how this data is sourced, computed, and verified.

Related

Browse all → | Rankings →
Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.