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NCT07287345 · ClinicalTrials.gov registry record · Phase 4
Colchicine's Effect on Inflammatory Markers
A Phase 4 study of Inflammatory Markers and Post Operative Atrial Fibrillation, sponsored by Ayesha Ather.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 24
- Enrollment target
- 1
- Study location
NCT07287345 is a Phase 4 study of Inflammatory Markers and Post Operative Atrial Fibrillation that is actively recruiting participants, run by Ayesha Ather. The registered enrollment target is 24 participants, below the 50-participant average among 3 other Inflammatory Markers trials with a reported enrollment target (52% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07287345, a Phase 4 study of Inflammatory Markers and Post Operative Atrial Fibrillation, is actively recruiting participants, sponsored by Ayesha Ather.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 24 participants
- Enrollment target
- 1
- Study location
Study Summary
This study wants to see if the medicine colchicine can help lower inflammation and reduce the chance of developing an irregular heartbeat (atrial fibrillation) after heart bypass surgery. Adults having coronary artery bypass surgery (CABG) can join. Participants will be randomly placed into one of two groups: one group will receive colchicine along with usual care, and the other will receive a placebo (a look-alike capsule with no medicine) along with usual care. Everyone will take a study capsule, and neither the patients nor the study team will know which capsule is being given. Everyone in the study will take study capsule, and neither the patients nor the study team will know who is receiving colchicine or placebo. Blood samples and health information will be collected before surgery; at 24, 48, 72, and 96 hours after surgery; and again at 10 days after surgery or at hospital discharge, whichever comes first. The investigators will look at inflammation marker levels, whether atrial fibrillation happens, and any side effects. This small study will help to generate effect size estimates and safety data that will help plan a larger study in the future.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Colchicine (Colcrys®)
Study Locations (1)
Kentucky
- University of Kentucy - Lexington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2026-01-16 |
| Est. Completion | 2026-06 |
| Phase | Phase 4 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07287345
The ClinicalTrials.gov registry entry for NCT07287345 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 50-participant average among 3 other Inflammatory Markers trials with a reported enrollment target (52% lower). The listed sponsor is Ayesha Ather, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 5 conditions, with Inflammatory Markers appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT07287345 reports 1 study location spanning 1 distinct geographic area - top geographies include Kentucky.
Frequently Asked Questions
What is clinical trial NCT07287345 about?
NCT07287345 is a clinical study titled "Colchicine's Effect on Inflammatory Markers". This study wants to see if the medicine colchicine can help lower inflammation and reduce the chance of developing an irregular heartbeat (atrial fibrillation) after heart bypass surgery. Adults having coronary artery bypass surgery (CABG) can join. Participants will be randomly placed into one of t...
What is the current status of trial NCT07287345?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 24 participants. The study started on 2026-01-16. Estimated completion is 2026-06.
What conditions does trial NCT07287345 study?
This clinical trial studies the following conditions: Inflammatory Markers, Post Operative Atrial Fibrillation, Colchicine, Inflammation in Cardiac Surgery, Colchicine Adverse Reaction.
What interventions are being tested in trial NCT07287345?
The interventions under investigation include: Placebo (DRUG), Colchicine (Colcrys®) (DRUG).
Who is sponsoring clinical trial NCT07287345?
This trial is sponsored by Ayesha Ather, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07287345 being conducted?
This trial has 1 study location across Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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