Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07286188 · ClinicalTrials.gov registry record · Phase 4
Effect of Misoprostol on Fluid Deficit Volume in Hysteroscopic Myomectomy
A Phase 4 study of Fibroids, Uterine and Fluid Deficit, sponsored by Northwestern University.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT07286188: Recruiting Phase 4 study of Fibroids, Uterine and Fluid Deficit, sponsored by Northwestern University.
NCT07286188 is a Phase 4 study of Fibroids, Uterine and Fluid Deficit that is actively recruiting participants, run by Northwestern University. The registered enrollment target is 40 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07286188, a Phase 4 study of Fibroids, Uterine and Fluid Deficit, is actively recruiting participants, sponsored by Northwestern University.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this double blinded randomized control trial is to evaluate the impact of misoprostol on fluid deficit during hysteroscopic myomectomies. The main questions it aims to answer are: Is there is difference in fluid deficit in patients who receive misoprostol vs placebo pre operatively for hysteroscopic myomectomies? Participants will be randomized to received 800 mcg of either rectal misoprostol prior to their hysteroscopic myomectomy or 4 tablets of placebo (ZEEBO) prior to their hysteroscopic myomectomy.
Primary Outcome
Primary outcome is difference in fluid deficit at the conclusion of the hysteroscopic myomectomy
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Misoprostol Tabets
Study Locations (1)
Illinois
- Northwestern - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2025-12-16 |
| Est. Completion | 2026-12 |
| Phase | Phase 4 |
What NCT07286188 shows while recruiting
NCT07286188 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower).
The record links to 3 conditions, with Fibroids, Uterine appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT07286188 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT07286188 about?
NCT07286188 is a clinical study titled "Effect of Misoprostol on Fluid Deficit Volume in Hysteroscopic Myomectomy". The goal of this double blinded randomized control trial is to evaluate the impact of misoprostol on fluid deficit during hysteroscopic myomectomies. The main questions it aims to answer are: Is there is difference in fluid deficit in patients who receive misoprostol vs placebo pre operatively for ...
What is the current status of trial NCT07286188?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 40 participants. The study started on 2025-12-16. Estimated completion is 2026-12.
What conditions does trial NCT07286188 study?
This clinical trial studies the following conditions: Fibroids, Uterine, Fluid Deficit, Hysteroscopy / Methods.
What interventions are being tested in trial NCT07286188?
The interventions under investigation include: Placebo (DRUG), Misoprostol Tabets (DRUG).
Who is sponsoring clinical trial NCT07286188?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07286188 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07286188's enrollment target sits among peer trials
40 1397th of 2000 higher than 534 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01306019 · 40 participants · Phase 1
Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)
- NCT01608152 · 40 participants
Development of a Video Game for the Improvement of Outcomes in Stem Cell Transplant Survivors
- NCT01668082 · 40 participants · NA
An Investigation of Brain Tumor Metabolism in Patients Undergoing Surgical Resection
- NCT02015013 · 40 participants · Phase 2
Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI