Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07276035 · ClinicalTrials.gov registry record · NA
Brain-Stomach Circuits in Chronic Nausea
A NA study of Chronic Nausea and Vomiting Syndrome, sponsored by David Levinthal.
- Recruiting
- Registry status
- NA
- Development phase
- 219
- Enrollment target
- 1
- Study location
NCT07276035: Recruiting NA study of Chronic Nausea and Vomiting Syndrome, sponsored by David Levinthal.
NCT07276035 is a NA study of Chronic Nausea and Vomiting Syndrome that is actively recruiting participants, run by David Levinthal. The registered enrollment target is 219 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (84% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07276035, a NA study of Chronic Nausea and Vomiting Syndrome, is actively recruiting participants, sponsored by David Levinthal.
- RECRUITING
- Registry status
- NA
- Development phase
- 219 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this study is to determine whether stimulation of the brain-stomach connection can influence stomach activity in healthy adults and in individuals suffering from chronic nausea. The main questions it aims to answer are: * What are the best brain sites to influence the stomach? * What are the effects of different stimulation patterns on stomach activity? * Does the stimulation affect the sensation of nausea in participants suffering from chronic nausea? Researchers will use a non-invasive method of brain stimulation called Transcranial Magnetic Stimulation (TMS) and will record stomach responses with skin electrodes on the abdomen. Participants will: * Visit the clinic at least once, and for up to 9 times more over the course of several months. * Receive TMS while sitting in a chair similar to a dentist's chair. * Drink water or consume a test meal during each study visit.
Primary Outcome
Location of GMEP hotspot(s) in M1 and/or premotor areas relative to FDI hotspot
Conditions Studied
Interventions
- DEVICE Transcranial Magnetic Stimulation, TMS
Study Locations (1)
Pennsylvania
- University of Pittsburgh Medical Center - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 219 participants |
| Start Date | 2026-01-28 |
| Est. Completion | 2031-07 |
| Phase | NA |
What NCT07276035 shows while recruiting
NCT07276035 is an interventional study that assigns participants to a tested intervention. The registered 219 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (84% lower).
The record links to 1 condition, with Chronic Nausea and Vomiting Syndrome appearing as the primary indexed condition, and to 1 intervention - of which Transcranial Magnetic Stimulation, TMS is the first listed.
NCT07276035 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT07276035 about?
NCT07276035 is a clinical study titled "Brain-Stomach Circuits in Chronic Nausea". The goal of this study is to determine whether stimulation of the brain-stomach connection can influence stomach activity in healthy adults and in individuals suffering from chronic nausea. The main questions it aims to answer are: * What are the best brain sites to influence the stomach? * What ar...
What is the current status of trial NCT07276035?
This trial is currently recruiting. It is a NA study. The enrollment target is 219 participants. The study started on 2026-01-28. Estimated completion is 2031-07.
What conditions does trial NCT07276035 study?
This clinical trial studies the following conditions: Chronic Nausea and Vomiting Syndrome.
What interventions are being tested in trial NCT07276035?
The interventions under investigation include: Transcranial Magnetic Stimulation, TMS (DEVICE).
Who is sponsoring clinical trial NCT07276035?
This trial is sponsored by David Levinthal, which has 3 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07276035 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07276035's enrollment target sits among peer trials
219 485th of 2000 higher than 1,516 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT05196035 · 219 participants · Phase 3
A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria
- NCT05608434 · 219 participants · Phase 1
Development of Virtual Reality-based Interventions to Strengthen Cognitive Skillsets Related to Attention Deficit Hyperactivity Disorder (ADHD): A Pilot Phase I and Randomized Controlled Phase II Trial
- NCT05773144 · 219 participants · NA
Adaptive Randomization of Aerobic Exercise During Chemotherapy in Colon Cancer
- NCT05907980 · 219 participants · Phase 1
A Phase I Study of ROSE12 Alone and in Combination With Other Anti-tumor Agents in Patients With Solid Tumors
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI