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NCT07260253 · ClinicalTrials.gov registry record · NA
Remotely-supervised Neuromodulation in PPA
A NA study of Primary Progressive Aphasia(PPA) and Logopenic Progressive Aphasia (LPA), sponsored by University of Texas at Austin.
- Recruiting
- Registry status
- NA
- Development phase
- 80
- Enrollment target
- 2
- Study locations
NCT07260253 is a NA study of Primary Progressive Aphasia(PPA) and Logopenic Progressive Aphasia (LPA) that is actively recruiting participants, run by University of Texas at Austin. The registered enrollment target is 80 participants. The trial reports 2 study locations across 2 states.
The verdict
NCT07260253, a NA study of Primary Progressive Aphasia(PPA) and Logopenic Progressive Aphasia (LPA), is actively recruiting participants, sponsored by University of Texas at Austin.
- RECRUITING
- Registry status
- NA
- Development phase
- 80 participants
- Enrollment target
- 2
- Study locations
Study Summary
The goal of this clinical trial is to learn whether remotely-supervised transcranial direct-current stimulation (RS-tDCS) can improve speech and language treatments for individuals with logopenic variant primary progressive aphasia (lvPPA). tDCS is a form of brain stimulation where a low-level electrical current is delivered to the brain through electrodes placed on the head. The main questions the trial aims to answer are: * Is it feasible to do RS-tDCS with virtual speech therapy? * How can brain magnetic resonance imaging scans (MRIs) predict how well someone will benefit from RS-tDCS with virtual speech therapy? Researchers will compare active RS-tDCS stimulation to sham stimulation (where there is no active stimulation, but participants feel stimulation effects at the beginning and end of the session). Participants will: * Travel to either the University of California, San Francisco (UCSF) or the University of Texas at Austin (UT Austin) one time for in-person testing, an MRI scan, and training on how to use the RS-tDCS equipment * Meet with a speech-language pathologist for pre-treatment testing on Zoom for 2 weeks * Participate in speech-language therapy and independent practice on Zoom 5 days a week for 4 weeks, using either active tDCS stimulation or sham * Complete post-treatment testing on Zoom for 1-2 weeks * Complete follow-up testing 2 months after completion of treatment
Conditions Studied
Interventions
- BEHAVIORAL Lexical Retrieval Cascade Treatment
- DEVICE Remotely Supervised Transcranial Direct Current Stimulation
Study Locations (2)
California
- UCSF Memory and Aging Cener - San Francisco
Texas
- University of Texas - Austin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2026-01 |
| Est. Completion | 2029-08 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07260253
The ClinicalTrials.gov registry entry for NCT07260253 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Texas at Austin, which has 257 total studies on file at ClinicalTrials.gov.
The record links to 6 conditions, with Primary Progressive Aphasia(PPA) appearing as the primary indexed condition, and to 2 interventions - of which Lexical Retrieval Cascade Treatment is the first listed.
NCT07260253 reports 2 study locations spanning 2 distinct geographic areas - top geographies include California, Texas.
Frequently Asked Questions
What is clinical trial NCT07260253 about?
NCT07260253 is a clinical study titled "Remotely-supervised Neuromodulation in PPA". The goal of this clinical trial is to learn whether remotely-supervised transcranial direct-current stimulation (RS-tDCS) can improve speech and language treatments for individuals with logopenic variant primary progressive aphasia (lvPPA). tDCS is a form of brain stimulation where a low-level elect...
What is the current status of trial NCT07260253?
This trial is currently recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2026-01. Estimated completion is 2029-08.
What conditions does trial NCT07260253 study?
This clinical trial studies the following conditions: Primary Progressive Aphasia(PPA), Logopenic Progressive Aphasia (LPA), Progressive Aphasia, Logopenic Variant Primary Progressive Aphasia, Logopenic Variant of Primary Progressive Aphasia (LPA).
What interventions are being tested in trial NCT07260253?
The interventions under investigation include: Lexical Retrieval Cascade Treatment (BEHAVIORAL), Remotely Supervised Transcranial Direct Current Stimulation (DEVICE).
Who is sponsoring clinical trial NCT07260253?
This trial is sponsored by University of Texas at Austin, which has 257 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07260253 being conducted?
This trial has 2 study locations across California, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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