Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07257120 · ClinicalTrials.gov registry record · Phase 4
KarXT Concentrations in the Breast Milk and Plasma of Lactating Females
A Phase 4 study of Healthy Volunteers, sponsored by Karuna Therapeutics.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 8
- Enrollment target
- 1
- Study location
NCT07257120 is a Phase 4 study of Healthy Volunteers that is actively recruiting participants, run by Karuna Therapeutics. The registered enrollment target is 8 participants, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07257120, a Phase 4 study of Healthy Volunteers, is actively recruiting participants, sponsored by Karuna Therapeutics.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 8 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to characterize the PK of xanomeline and trospium in breast milk and plasma in healthy lactating female participants, following multiple oral administration of KarXT in healthy lactating participants.
Conditions Studied
Interventions
- DRUG Xanomeline/trospium chloride
Study Locations (1)
Nevada
- PPD | Las Vegas Clinical Research Unit - Las Vegas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2026-01-09 |
| Est. Completion | 2027-11-30 |
| Phase | Phase 4 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07257120
The ClinicalTrials.gov registry entry for NCT07257120 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 8 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (98% lower). The listed sponsor is Karuna Therapeutics, which has 11 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Healthy Volunteers appearing as the primary indexed condition, and to 1 intervention - of which Xanomeline/trospium chloride is the first listed.
NCT07257120 reports 1 study location spanning 1 distinct geographic area - top geographies include Nevada.
Frequently Asked Questions
What is clinical trial NCT07257120 about?
NCT07257120 is a clinical study titled "KarXT Concentrations in the Breast Milk and Plasma of Lactating Females". The purpose of this study is to characterize the PK of xanomeline and trospium in breast milk and plasma in healthy lactating female participants, following multiple oral administration of KarXT in healthy lactating participants.
What is the current status of trial NCT07257120?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 8 participants. The study started on 2026-01-09. Estimated completion is 2027-11-30.
What conditions does trial NCT07257120 study?
This clinical trial studies the following conditions: Healthy Volunteers.
What interventions are being tested in trial NCT07257120?
The interventions under investigation include: Xanomeline/trospium chloride (DRUG).
Who is sponsoring clinical trial NCT07257120?
This trial is sponsored by Karuna Therapeutics, which has 11 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07257120 being conducted?
This trial has 1 study location across Nevada. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy Volunteers
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Effects of Energy Drinks on Cardiovascular Endpoints
RECRUITING · Phase 4
-
Investigation of the Gut Microbiome and Statin Response
ACTIVE NOT RECRUITING · Phase 4
-
Thorough QT Study of Nelfinavir
COMPLETED · Phase 4
-
A Study to Investigate Cardiac Troponin Levels After mRNA-1273.712 Vaccine in Participants 12 Through 30 Years of Age
COMPLETED · Phase 4
-
Annual Study for Collection of Serum Samples in Children and Older Adults Receiving the 2021-2022 Formulations of Fluzone Quadrivalent Vaccine and Fluzone High-Dose Quadrivalent Vaccine, Respectively
COMPLETED · Phase 4
-
Adaptive Optics Retinal Imaging
RECRUITING
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.