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NCT07228286 · ClinicalTrials.gov registry record · Early Phase 1
REstoring CONsciousness With NEurostimulation of the Central Thalamus: The RECONNECT Study
A Early Phase 1 study of Disorders of Consciousness, sponsored by Samuel Snider, MD.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 2
- Enrollment target
- 1
- Study location
NCT07228286: Recruiting Early Phase 1 study of Disorders of Consciousness, sponsored by Samuel Snider, MD.
NCT07228286 is a Early Phase 1 study of Disorders of Consciousness that is actively recruiting participants, run by Samuel Snider, MD. The registered enrollment target is 2 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07228286, a Early Phase 1 study of Disorders of Consciousness, is actively recruiting participants, sponsored by Samuel Snider, MD.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 2 participants
- Enrollment target
- 1
- Study location
Study Summary
The RE-CONNECT study is an early feasibility study to establish the safety, feasibility, and efficacy of two central thalamic deep brain stimulation targets in patients with chronic disorders of consciousness.
Primary Outcome
Behavioral scale for patients wth DoC. Range: 0 to 23 with higher values indicating greater levels of awareness.
Conditions Studied
Interventions
- DEVICE Deep brain stimulation (DBS) electrode implantation
Study Locations (1)
Massachusetts
- Brigham and Women's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2025-11-10 |
| Est. Completion | 2029-02-10 |
| Phase | Early Phase 1 |
What NCT07228286 shows while recruiting
NCT07228286 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Disorders of Consciousness appearing as the primary indexed condition, and to 1 intervention - of which Deep brain stimulation (DBS) electrode implantation is the first listed.
NCT07228286 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT07228286 about?
NCT07228286 is a clinical study titled "REstoring CONsciousness With NEurostimulation of the Central Thalamus: The RECONNECT Study". The RE-CONNECT study is an early feasibility study to establish the safety, feasibility, and efficacy of two central thalamic deep brain stimulation targets in patients with chronic disorders of consciousness.
What is the current status of trial NCT07228286?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 2 participants. The study started on 2025-11-10. Estimated completion is 2029-02-10.
What conditions does trial NCT07228286 study?
This clinical trial studies the following conditions: Disorders of Consciousness.
What interventions are being tested in trial NCT07228286?
The interventions under investigation include: Deep brain stimulation (DBS) electrode implantation (DEVICE).
Who is sponsoring clinical trial NCT07228286?
This trial is sponsored by Samuel Snider, MD, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07228286 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07228286's enrollment target sits among peer trials
2 1974th of 2000 higher than 16 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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