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NCT07227753 · ClinicalTrials.gov registry record

The Association Between Gut Microbiota Diversity and Postpartum Depression

A clinical trial of Depression During Pregnancy, sponsored by Massachusetts General Hospital.

Recruiting
Registry status
30
Enrollment target
1
Study location

NCT07227753 is a study of Depression During Pregnancy that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 30 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT07227753, a study of Depression During Pregnancy, is actively recruiting participants, sponsored by Massachusetts General Hospital.

RECRUITING
Registry status
30 participants
Enrollment target
1
Study location

Study Summary

This study aims to examine whether naturally occurring bacteria in the gastrointestinal tract are associated with mood changes following childbirth, including postpartum depression. Biological samples will be collected before and after delivery to determine whether specific patterns in gut bacterial composition are linked to emotional states. The purpose of the research is to improve understanding of whether such microbial changes can help identify individuals at higher risk for postpartum depression, enabling earlier recognition and intervention.

Study Locations (1)

Massachusetts

  • Meikun Wang - Boston

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2025-11-17
Est. Completion 2026-05

Sponsor

Massachusetts General Hospital

2,032 total trials

What the Registry Record Tells You About NCT07227753

The ClinicalTrials.gov registry entry for NCT07227753 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Depression During Pregnancy appearing as the primary indexed condition, and to 0 interventions.

NCT07227753 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT07227753 about?

NCT07227753 is a clinical study titled "The Association Between Gut Microbiota Diversity and Postpartum Depression". This study aims to examine whether naturally occurring bacteria in the gastrointestinal tract are associated with mood changes following childbirth, including postpartum depression. Biological samples will be collected before and after delivery to determine whether specific patterns in gut bacterial...

What is the current status of trial NCT07227753?

This trial is currently recruiting. The enrollment target is 30 participants. The study started on 2025-11-17. Estimated completion is 2026-05.

What conditions does trial NCT07227753 study?

This clinical trial studies the following conditions: Depression During Pregnancy.

Who is sponsoring clinical trial NCT07227753?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07227753 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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