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NCT07226258 · ClinicalTrials.gov registry record · Phase 3
Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain
A Phase 3 study of Osteoarthritis Knee Pain, sponsored by Saol Therapeutics.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 150
- Enrollment target
- 13
- Study locations
NCT07226258: Recruiting Phase 3 study of Osteoarthritis Knee Pain, sponsored by Saol Therapeutics.
NCT07226258 is a Phase 3 study of Osteoarthritis Knee Pain that is actively recruiting participants, run by Saol Therapeutics. The registered enrollment target is 150 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (81% lower). The trial reports 13 study locations across 9 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07226258, a Phase 3 study of Osteoarthritis Knee Pain, is actively recruiting participants, sponsored by Saol Therapeutics.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 150 participants
- Enrollment target
- 13
- Study locations
Study Summary
A Randomized, Double-Blind, Placebo-Controlled, Single Dose Study to Assess the Safety and Efficacy of SL1002 for the Treatment of Knee Pain in Patients with Osteoarthritis of the Knee.
Primary Outcome
The pain intensity score is measured using a numeric rating scale (NRS)
Conditions Studied
Interventions
- DRUG Normal Saline
- DRUG SL1002
Study Locations (13)
Florida
- Prime Medical Research - Coral Gables
- Conquest Research, LLC - Orlando
- Conquest Research, LLC - Winter Park
North Carolina
- Queen City Clinical Research, PLLC - Charlotte
- The Center for Clinical Research - Winston-Salem
Texas
- HD Research, First Surgical Hospital (FSH) - Bellaire
- Institute of Precision Pain Medicine - Corpus Christi
Colorado
- DBPS Research, LLC - Greenwood Village
District of Columbia
- International Spine, Pain & Performance Center - Washington D.C.
Oregon
- Pacific Sports and Spine - Eugene
Pennsylvania
- University Orthopedics Center - Altoona
South Carolina
- PCPMG Clinical Research Unit, LLC - Greenville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2025-11-07 |
| Est. Completion | 2027-02-28 |
| Phase | Phase 3 |
What NCT07226258 shows while recruiting
NCT07226258 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (81% lower).
The record links to 1 condition, with Osteoarthritis Knee Pain appearing as the primary indexed condition, and to 2 interventions - of which Normal Saline is the first listed.
NCT07226258 lists 13 locations in 9 states (Florida, North Carolina, Texas).
Frequently Asked Questions
What is clinical trial NCT07226258 about?
NCT07226258 is a clinical study titled "Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain". A Randomized, Double-Blind, Placebo-Controlled, Single Dose Study to Assess the Safety and Efficacy of SL1002 for the Treatment of Knee Pain in Patients with Osteoarthritis of the Knee.
What is the current status of trial NCT07226258?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 150 participants. The study started on 2025-11-07. Estimated completion is 2027-02-28.
What conditions does trial NCT07226258 study?
This clinical trial studies the following conditions: Osteoarthritis Knee Pain.
What interventions are being tested in trial NCT07226258?
The interventions under investigation include: Normal Saline (DRUG), SL1002 (DRUG).
Who is sponsoring clinical trial NCT07226258?
This trial is sponsored by Saol Therapeutics, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07226258 being conducted?
This trial has 13 study locations across Colorado, District of Columbia, Florida, North Carolina, Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Osteoarthritis Knee Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07226258's enrollment target sits among peer trials
150 1520th of 2000 higher than 455 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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