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NCT07225348 · ClinicalTrials.gov registry record · Phase 4
Treatment of Perioral Wrinkles Using Topical Poly-L-lactic Acid and Microneedling Device
A Phase 4 study of Perioral Wrinkles, sponsored by Skincare Physicians of Chestnut Hill.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 26
- Enrollment target
- 1
- Study location
NCT07225348 is a Phase 4 study of Perioral Wrinkles that is actively recruiting participants, run by Skincare Physicians of Chestnut Hill. The registered enrollment target is 26 participants. The trial reports 1 study location across 1 state.
The verdict
NCT07225348, a Phase 4 study of Perioral Wrinkles, is actively recruiting participants, sponsored by Skincare Physicians of Chestnut Hill.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 26 participants
- Enrollment target
- 1
- Study location
Study Summary
The first goal of this clinical trial is to learn if topical application of PLLA in conjunction with a microneedling treatment works to treat perioral wrinkles in adults. The second goal is to see whether the application of topical PLLA is more effective before or after a microneedling treatment. The main questions it aims to answer are: * Is PLLA present within the MN channels from in vivo biopsy samples? * Is it safe to combine topical PLLA and MN in the treatment of perioral wrinkles, as determined by the incidence and severity of adverse events in healthy subjects? * Does overall aesthetic and skin texture improve in combining microneedling with topical PLLA in the treatment of mild to moderate perioral wrinkles? * Is it the treatment of topical PLLA more effective when applied before or after a microneedling treatment. Researchers will compare the application of PLLA before a microneedling treatment to a microneedling treatment with PLLA application after to see which treatment method is more effective. Participants will: \- receive 2 treatments spaced 4-6 weeks apart of topical PLLA and microneedling
Conditions Studied
Interventions
- DRUG Poly-L-Lactic Acid
- DEVICE Microneedling
Study Locations (1)
Massachusetts
- SkinCare Physicians - Chestnut Hill
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 26 participants |
| Start Date | 2025-11-07 |
| Est. Completion | 2026-10-01 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07225348
The ClinicalTrials.gov registry entry for NCT07225348 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 26 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Skincare Physicians of Chestnut Hill, which has 2 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Perioral Wrinkles appearing as the primary indexed condition, and to 2 interventions - of which Poly-L-Lactic Acid is the first listed.
NCT07225348 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.
Frequently Asked Questions
What is clinical trial NCT07225348 about?
NCT07225348 is a clinical study titled "Treatment of Perioral Wrinkles Using Topical Poly-L-lactic Acid and Microneedling Device". The first goal of this clinical trial is to learn if topical application of PLLA in conjunction with a microneedling treatment works to treat perioral wrinkles in adults. The second goal is to see whether the application of topical PLLA is more effective before or after a microneedling treatment. Th...
What is the current status of trial NCT07225348?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 26 participants. The study started on 2025-11-07. Estimated completion is 2026-10-01.
What conditions does trial NCT07225348 study?
This clinical trial studies the following conditions: Perioral Wrinkles.
What interventions are being tested in trial NCT07225348?
The interventions under investigation include: Poly-L-Lactic Acid (DRUG), Microneedling (DEVICE).
Who is sponsoring clinical trial NCT07225348?
This trial is sponsored by Skincare Physicians of Chestnut Hill, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07225348 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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