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RECRUITING Phase 1

An Investigational Study of BG-75202 Alone and in Combination With Other Therapeutic Agents in Adults With Advanced Solid Tumors

NCT07222267 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics, and preliminary antitumor activity of BG-75202 (KAT6A/B inhibitor) alone and in combination with other therapies in participants with breast cancer and other advanced solid tumors.

Interventions

  • DRUG Aromatase Inhibitor
  • DRUG BG-75202
  • DRUG CDK4 Inhibitor
  • DRUG Estrogen Receptor Antagonist

Study Locations (12)

Texas

  • Next Oncology Austin — Austin
  • The University of Texas Md Anderson Cancer Center — Houston

Beijing Municipality

  • Cancer Hospital Chinese Academy of Medical Sciences — Beijing
  • Beijing Cancer Hospital — Beijing

Missouri

  • Washington University in St Louis — St Louis

New South Wales

  • Blacktown Cancer and Haematology Centre — Blacktown

South Australia

  • Cancer Research South Australia — Adelaide

Victoria

  • Peter Maccallum Cancer Centre — Melbourne

Guangdong

  • Sun Yat Sen University Cancer Centerhuangpu Branch — Guangzhou

Jiangsu

  • Jiangsu Province Hospital Longjiang Branch — Nanjing

Trial Details

FieldValue
Enrollment Target 86 participants
Start Date 2025-12-11
Est. Completion 2037-01-13
Phase Phase 1

Sponsor

BeOne Medicines

138 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07222267

The ClinicalTrials.gov registry entry for NCT07222267 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 86 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is BeOne Medicines, which has 138 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Breast Cancer appearing as the primary indexed condition, and to 4 interventions — of which Aromatase Inhibitor is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07222267 reports 12 study locations spanning 10 distinct geographic areas — top geographies include Texas, Beijing Municipality, Missouri. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07222267 about?

NCT07222267 is a clinical study titled "An Investigational Study of BG-75202 Alone and in Combination With Other Therapeutic Agents in Adults With Advanced Solid Tumors". The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics, and preliminary antitumor activity of BG-75202 (KAT6A/B inhibitor) alone and in combination with other therapies in participants with breast cancer and other advanced solid tumors.

What is the current status of trial NCT07222267?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 86 participants. The study started on 2025-12-11. Estimated completion is 2037-01-13.

What conditions does trial NCT07222267 study?

This clinical trial studies the following conditions: Breast Cancer, Advanced Solid Tumor. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07222267?

The interventions under investigation include: Aromatase Inhibitor (DRUG), BG-75202 (DRUG), CDK4 Inhibitor (DRUG), Estrogen Receptor Antagonist (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07222267?

This trial is sponsored by BeOne Medicines, which has 138 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07222267 being conducted?

This trial has 12 study locations across Missouri, Texas, New South Wales, South Australia, Victoria. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial