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NCT07221786 · ClinicalTrials.gov registry record · NA
Preoperative Opioid Tapering Before Spine Surgery
A NA study of Opioid Dependency and Opioid Consumption, Postoperative, sponsored by Thomas Jefferson University.
- Recruiting
- Registry status
- NA
- Development phase
- 45
- Enrollment target
- 1
- Study location
NCT07221786: Recruiting NA study of Opioid Dependency and Opioid Consumption, Postoperative, sponsored by Thomas Jefferson University.
NCT07221786 is a NA study of Opioid Dependency and Opioid Consumption, Postoperative that is actively recruiting participants, run by Thomas Jefferson University. The registered enrollment target is 45 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07221786, a NA study of Opioid Dependency and Opioid Consumption, Postoperative, is actively recruiting participants, sponsored by Thomas Jefferson University.
- RECRUITING
- Registry status
- NA
- Development phase
- 45 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a pilot study in which patients taking opioids chronically who are scheduled for spine surgery at least 4 weeks in advance will be randomly assigned to one of two groups: opioid tapering with education alone or opioid tapering with education plus cognitive behavioral therapy (CBT). The primary objective is to determine the proportion of each group that is successful in achieving their opioid tapering goals by the time of surgery.
Primary Outcome
Achievement of the opioid tapering goal for each patient will be assessed on day of surgery and will be based on average daily OMEs taken during the three days before surgery. The opioid tapering goal will be made on the initial visit with the study pain physician and will be specific to each patient.
Conditions Studied
Interventions
- OTHER Opioid tapering with CBT and education
- OTHER Opioid tapering with education alone
Study Locations (1)
Pennsylvania
- Thomas Jefferson University Hospital - Philadephia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 45 participants |
| Start Date | 2025-12-01 |
| Est. Completion | 2026-12 |
| Phase | NA |
What NCT07221786 shows while recruiting
NCT07221786 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 45 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 3 conditions, with Opioid Dependency appearing as the primary indexed condition, and to 2 interventions - of which Opioid tapering with CBT and education is the first listed.
NCT07221786 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT07221786 about?
NCT07221786 is a clinical study titled "Preoperative Opioid Tapering Before Spine Surgery". This is a pilot study in which patients taking opioids chronically who are scheduled for spine surgery at least 4 weeks in advance will be randomly assigned to one of two groups: opioid tapering with education alone or opioid tapering with education plus cognitive behavioral therapy (CBT). The prima...
What is the current status of trial NCT07221786?
This trial is currently recruiting. It is a NA study. The enrollment target is 45 participants. The study started on 2025-12-01. Estimated completion is 2026-12.
What conditions does trial NCT07221786 study?
This clinical trial studies the following conditions: Opioid Dependency, Opioid Consumption, Postoperative, Pain After Surgery.
What interventions are being tested in trial NCT07221786?
The interventions under investigation include: Opioid tapering with CBT and education (OTHER), Opioid tapering with education alone (OTHER).
Who is sponsoring clinical trial NCT07221786?
This trial is sponsored by Thomas Jefferson University, which has 292 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07221786 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07221786's enrollment target sits among peer trials
45 1411th of 2000 higher than 578 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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