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NCT07221539 · ClinicalTrials.gov registry record · NA
Restoration of Consciousness With Ultrasonic Deep Brain Stimulation During Anesthetic Sedation
A NA study of Mental Function, sponsored by University of Michigan.
- Recruiting
- Registry status
- NA
- Development phase
- 168
- Enrollment target
- 1
- Study location
NCT07221539 is a NA study of Mental Function that is actively recruiting participants, run by University of Michigan. The registered enrollment target is 168 participants. The trial reports 1 study location across 1 state.
The verdict
NCT07221539, a NA study of Mental Function, is actively recruiting participants, sponsored by University of Michigan.
- RECRUITING
- Registry status
- NA
- Development phase
- 168 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to see if mental functions take place during different levels of anesthesia using two commonly used drug (propofol and dexmedetomidine) and will include low-intensity focused ultrasound pulsation (LIFUP) to stimulate specific areas of the brain while undergoing functional Magnetic Resonance Imaging (fMRI or "brain imaging"), which shows areas in the brain involved in thinking at different depths of anesthesia. That is, ultrasound is being used to stimulate the brain and multiple pictures will be taken of the brain. As a result of this study, we expect to gain a deeper understanding of mental function during different levels of anesthesia, and to evaluate if the use of ultrasonic brain stimulation accelerates return to consciousness.
Conditions Studied
Interventions
- PROCEDURE Propofol for fMRI
- PROCEDURE Dexmedetomidine for fMRI
- DEVICE Dorsolateral prefrontal cortex (DLPFC) pulsation
- DEVICE Anterior insular cortex (AIC) pulsation
- DEVICE Central thalamus (CT) pulsation
Study Locations (1)
Michigan
- University of Michigan - Ann Arbor
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 168 participants |
| Start Date | 2025-10-24 |
| Est. Completion | 2030-10 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07221539
The ClinicalTrials.gov registry entry for NCT07221539 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 168 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Michigan, which has 1,327 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Mental Function appearing as the primary indexed condition, and to 5 interventions - of which Propofol for fMRI is the first listed.
NCT07221539 reports 1 study location spanning 1 distinct geographic area - top geographies include Michigan.
Frequently Asked Questions
What is clinical trial NCT07221539 about?
NCT07221539 is a clinical study titled "Restoration of Consciousness With Ultrasonic Deep Brain Stimulation During Anesthetic Sedation". The purpose of this study is to see if mental functions take place during different levels of anesthesia using two commonly used drug (propofol and dexmedetomidine) and will include low-intensity focused ultrasound pulsation (LIFUP) to stimulate specific areas of the brain while undergoing functiona...
What is the current status of trial NCT07221539?
This trial is currently recruiting. It is a NA study. The enrollment target is 168 participants. The study started on 2025-10-24. Estimated completion is 2030-10.
What conditions does trial NCT07221539 study?
This clinical trial studies the following conditions: Mental Function.
What interventions are being tested in trial NCT07221539?
The interventions under investigation include: Propofol for fMRI (PROCEDURE), Dexmedetomidine for fMRI (PROCEDURE), Dorsolateral prefrontal cortex (DLPFC) pulsation (DEVICE), Anterior insular cortex (AIC) pulsation (DEVICE), Central thalamus (CT) pulsation (DEVICE).
Who is sponsoring clinical trial NCT07221539?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07221539 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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