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NCT07220239 · ClinicalTrials.gov registry record · NA
Menstrual Cup for Early Endometrial Cancer Detection in Lynch Syndrome
A NA study of Endometrial Cancer and Lynch Syndrome, sponsored by Jessica D. St. Laurent, MD.
- Recruiting
- Registry status
- NA
- Development phase
- 25
- Enrollment target
- 1
- Study location
NCT07220239: Recruiting NA study of Endometrial Cancer and Lynch Syndrome, sponsored by Jessica D. St. Laurent, MD.
NCT07220239 is a NA study of Endometrial Cancer and Lynch Syndrome that is actively recruiting participants, run by Jessica D. St. Laurent, MD. The registered enrollment target is 25 participants, below the 524-participant average among 181 other Endometrial Cancer trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07220239, a NA study of Endometrial Cancer and Lynch Syndrome, is actively recruiting participants, sponsored by Jessica D. St. Laurent, MD.
- RECRUITING
- Registry status
- NA
- Development phase
- 25 participants
- Enrollment target
- 1
- Study location
Study Summary
Study Goal: This pilot study wants to find out if using a menstrual cup can be a good, non-invasive way to collect samples from the lining of the uterus (called the endometrium) to help screen for endometrial cancer. This is especially important for women who have a higher chance of getting this cancer, such as those with a genetic condition called Lynch syndrome. Main Questions the Study Will Answer: 1. Can a menstrual cup collect enough uterine lining (endometrial tissue) for doctors to examine under a microscope? 2. Are the samples from the menstrual cup as useful for diagnosis as samples taken using the usual method (called an endometrial biopsy or EMB)? 3. Is using a menstrual cup at home easy, effective, and comfortable for participants? 4. Can scientists grow small lab models of the uterus (called organoids) from the menstrual cup samples and from biopsy samples? What Will Happen in the Study: * Participants will use a menstrual cup at home to collect menstrual blood. * They will also have a standard endometrial biopsy done by a healthcare provider. * After both collections, participants will fill out a short survey about how comfortable and easy it was to use the menstrual cup. What the Study Will Measure: * Feasibility: How well participants are able to use the menstrual cup and send in the sample. * Sample Quality: Whether the menstrual cup collects enough good-quality tissue for testing, and how it compares to biopsy samples. * Participant Experience: How women feel about using the menstrual cup, based on the survey. * Lab Testing: Whether researchers can successfully grow endometrial organoids from both types of samples. Why This Study Matters: If this method works, it could offer a gentler, more convenient way for women to get checked for endometrial cancer-especially those who need regular screening. It could also make it easier to collect samples for research and improve early detection of cancer.
Primary Outcome
A pathologist will evaluate the menstrual cup-based sample and record its adequacy for pathological evaluation using a questionnaire with binary responses.
Conditions Studied
Interventions
- DEVICE Menstrual cup use
Study Locations (1)
Massachusetts
- Dana-Farber Cancer Institute - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2025-11-20 |
| Est. Completion | 2026-09 |
| Phase | NA |
What NCT07220239 shows while recruiting
NCT07220239 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 524-participant average among 181 other Endometrial Cancer trials with a reported enrollment target (95% lower).
The record links to 4 conditions, with Endometrial Cancer appearing as the primary indexed condition, and to 1 intervention - of which Menstrual cup use is the first listed.
NCT07220239 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT07220239 about?
NCT07220239 is a clinical study titled "Menstrual Cup for Early Endometrial Cancer Detection in Lynch Syndrome". Study Goal: This pilot study wants to find out if using a menstrual cup can be a good, non-invasive way to collect samples from the lining of the uterus (called the endometrium) to help screen for endometrial cancer. This is especially important for women who have a higher chance of getting this ca...
What is the current status of trial NCT07220239?
This trial is currently recruiting. It is a NA study. The enrollment target is 25 participants. The study started on 2025-11-20. Estimated completion is 2026-09.
What conditions does trial NCT07220239 study?
This clinical trial studies the following conditions: Endometrial Cancer, Lynch Syndrome, Early Detection of Cancer, Screening.
What interventions are being tested in trial NCT07220239?
The interventions under investigation include: Menstrual cup use (DEVICE).
Who is sponsoring clinical trial NCT07220239?
This trial is sponsored by Jessica D. St. Laurent, MD, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07220239 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Endometrial Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07220239's enrollment target sits among peer trials
25 158th of 181 higher than 21 of 181 other Endometrial Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Endometrial Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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