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NCT07218081 · ClinicalTrials.gov registry record · Phase 1
A Trial to Test Intermittent Deep Brain Stimulation of Nucleus Basalis of Meynert to Treat Alzheimers.
A Phase 1 study of Alzheimer Dementia (AD), sponsored by Augusta University.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 12
- Enrollment target
- 1
- Study location
NCT07218081 is a Phase 1 study of Alzheimer Dementia (AD) that is actively recruiting participants, run by Augusta University. The registered enrollment target is 12 participants. The trial reports 1 study location across 1 state.
The verdict
NCT07218081, a Phase 1 study of Alzheimer Dementia (AD), is actively recruiting participants, sponsored by Augusta University.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to test a new procedure to treat Alzheimer's disease. The procedure is called intermittent Deep Brain Stimulation (DBS) of the nucleus basalis of Meynert. There will be up to six participants enrolled at Wellstar MCG Memory Clinic. There will be another six participants similarly enrolled to act as a control group that does not receive DBS. This second group will document the course of progression of Alzheimer's disease under the normal standard of care. The main goal of the study is to determine if DBS can sustain or improve cognition in Alzheimer's disease for at least two years. Participant data, with identifying information removed, may be shared with online repositories for comparison with trials with similar subjects.
Conditions Studied
Interventions
- DEVICE Intermittent deep brain stimulation of the nucleus basalis of Meynert
Study Locations (1)
Georgia
- Wellstar MCG Hospital, Neurology Memory Clinic - Augusta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2026-02-01 |
| Est. Completion | 2028-11 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07218081
The ClinicalTrials.gov registry entry for NCT07218081 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Augusta University, which has 106 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Alzheimer Dementia (AD) appearing as the primary indexed condition, and to 1 intervention - of which Intermittent deep brain stimulation of the nucleus basalis of Meynert is the first listed.
NCT07218081 reports 1 study location spanning 1 distinct geographic area - top geographies include Georgia.
Frequently Asked Questions
What is clinical trial NCT07218081 about?
NCT07218081 is a clinical study titled "A Trial to Test Intermittent Deep Brain Stimulation of Nucleus Basalis of Meynert to Treat Alzheimers.". The purpose of this study is to test a new procedure to treat Alzheimer's disease. The procedure is called intermittent Deep Brain Stimulation (DBS) of the nucleus basalis of Meynert. There will be up to six participants enrolled at Wellstar MCG Memory Clinic. There will be another six participants ...
What is the current status of trial NCT07218081?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2026-02-01. Estimated completion is 2028-11.
What conditions does trial NCT07218081 study?
This clinical trial studies the following conditions: Alzheimer Dementia (AD).
What interventions are being tested in trial NCT07218081?
The interventions under investigation include: Intermittent deep brain stimulation of the nucleus basalis of Meynert (DEVICE).
Who is sponsoring clinical trial NCT07218081?
This trial is sponsored by Augusta University, which has 106 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07218081 being conducted?
This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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