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NCT07217626 · ClinicalTrials.gov registry record · Phase 4
Pre-Incision Peripheral Nerve Blocks for Lower Extremity Fracture Surgery in Older Adults
A Phase 4 study, sponsored by University of Maryland, Baltimore.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 34
- Enrollment target
NCT07217626: Recruiting Phase 4 study, sponsored by University of Maryland, Baltimore.
NCT07217626 is a Phase 4 study that is actively recruiting participants, run by University of Maryland, Baltimore. The registered enrollment target is 34 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07217626, a Phase 4 study, is actively recruiting participants, sponsored by University of Maryland, Baltimore.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 34 participants
- Enrollment target
Study Summary
Fractures of the lower leg are especially difficult for older adults. They are more likely to have serious complications, require longer healing times, and have a higher risk of death This occurs because their bodies cannot tolerate stress as well as younger individuals. The injury itself places significant strain on the body, and surgery adds additional stress. Anesthesiologists use nerve blocks to help manage pain during and after these injuries. A nerve block is an injection that numbs the fracture and surgery area by blocking pain signals. These injections help patients need fewer opioid medications. However, new research shows these nerve blocks may provide benefits beyond pain management. Studies looking at older adults with hip fractures who received nerve blocks showed better overall outcomes: fewer deaths, fewer serious complications, and shorter hospital stays. However, it is not currently known if nerve blocks work this well for other broken bones in the leg, like in the thigh or shin. Additional research is need to know if nerve blocks can help patients with all types of leg fractures recover faster and experience fewer problems. Before the investigators start a large clinical trial, a small pilot study needs to be completed to determine if a larger clinical trial is feasible. This pilot study will evaluate the ability to recruit enough patients, ensure patients can receive the assigned treatment, collect data effectively, follow the study protocol, and track participants over time. The results will indicate whether the investigators are prepared to proceed with a full-scale trial and help refine the approach.
Primary Outcome
Participant enrollment will be assessed by monitoring screening and enrollment metrics, including: * Initiation of screening and recruitment at the clinical site * Ability of the clinical site to screen consecutive patients 50 years of age and older with lower extremity fractures * Proportion of patients who are screened for eligibility to participate in the trial * Proportion of patients who meet the eligibility criteria * Review of reasons for exclusion * Proportion of patients who provide in
Interventions
- DRUG Local anesthesia injections
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 34 participants |
| Start Date | 2026-02-24 |
| Est. Completion | 2026-12-31 |
| Phase | Phase 4 |
What NCT07217626 shows while recruiting
NCT07217626 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 34 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 1 intervention - of which Local anesthesia injections is the first listed.
NCT07217626 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07217626 about?
NCT07217626 is a clinical study titled "Pre-Incision Peripheral Nerve Blocks for Lower Extremity Fracture Surgery in Older Adults". Fractures of the lower leg are especially difficult for older adults. They are more likely to have serious complications, require longer healing times, and have a higher risk of death This occurs because their bodies cannot tolerate stress as well as younger individuals. The injury itself places sig...
What is the current status of trial NCT07217626?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 34 participants. The study started on 2026-02-24. Estimated completion is 2026-12-31.
What interventions are being tested in trial NCT07217626?
The interventions under investigation include: Local anesthesia injections (DRUG).
Who is sponsoring clinical trial NCT07217626?
This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07217626's enrollment target sits among peer trials
34 1520th of 2000 higher than 473 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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