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NCT07216131 · ClinicalTrials.gov registry record · Phase 1
A Study to Investigate the Effect of AZD0780 on Metformin Pharmacokinetics in Healthy Adult Volunteers Aged 18 to 55 Years
A Phase 1 study, sponsored by AstraZeneca.
- Completed
- Registry status
- Phase 1
- Development phase
- 14
- Enrollment target
NCT07216131: Completed Phase 1 study, sponsored by AstraZeneca.
NCT07216131 is a Phase 1 study that has completed, run by AstraZeneca. The registered enrollment target is 14 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (77% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07216131, a Phase 1 study, has completed, sponsored by AstraZeneca.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 14 participants
- Enrollment target
Study Summary
The purpose of this study is to determine how the experimental medication AZD0780 impacts the pharmacokinetics (PK) of metformin, a common medication used to treat type 2 diabetes mellitus, when given together in healthy participants.
Primary Outcome
To assess the effect of AZD0780 on the PK of metformin.
Interventions
- DRUG Metformin
- DRUG AZD0780
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 14 participants |
| Start Date | 2025-11-10 |
| Est. Completion | 2025-12-30 |
| Phase | Phase 1 |
What the finished NCT07216131 record still lists
NCT07216131 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (77% lower).
The record links to 0 conditions, and to 2 interventions - of which Metformin is the first listed.
NCT07216131 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07216131 about?
NCT07216131 is a clinical study titled "A Study to Investigate the Effect of AZD0780 on Metformin Pharmacokinetics in Healthy Adult Volunteers Aged 18 to 55 Years". The purpose of this study is to determine how the experimental medication AZD0780 impacts the pharmacokinetics (PK) of metformin, a common medication used to treat type 2 diabetes mellitus, when given together in healthy participants.
What is the current status of trial NCT07216131?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 14 participants. The study started on 2025-11-10. Estimated completion is 2025-12-30.
What interventions are being tested in trial NCT07216131?
The interventions under investigation include: Metformin (DRUG), AZD0780 (DRUG).
Who is sponsoring clinical trial NCT07216131?
This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07216131's enrollment target sits among peer trials
14 1844th of 2000 higher than 154 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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