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NCT07206797 · ClinicalTrials.gov registry record · NA
Ultrasound for Quantifying Muscle Activation Elicited by Spinal Cord Stimulation and Functional Electrical Stimulation
A NA study of Neuromodulatory Effects of TSCS and FES in Lower Limbs, sponsored by North Carolina State University.
- Recruiting
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT07206797: Recruiting NA study of Neuromodulatory Effects of TSCS and FES in Lower Limbs, sponsored by North Carolina State University.
NCT07206797 is a NA study of Neuromodulatory Effects of TSCS and FES in Lower Limbs that is actively recruiting participants, run by North Carolina State University. The registered enrollment target is 30 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07206797, a NA study of Neuromodulatory Effects of TSCS and FES in Lower Limbs, is actively recruiting participants, sponsored by North Carolina State University.
- RECRUITING
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
Transcutaneous (non-invasive) spinal cord stimulation (tSCS) has been shown to facilitate volitional motor activity in patients with spinal cord injury. tSCS is known to activate the same neural structures as invasive SCS, meaning it may have the potential for functional restoration without an expensive surgical implant. Functional electrical stimulation (FES) is also used in therapy for patients with spinal cord injury to locally activate paralyzed or weakened muscles. There is evidence that combining FES and tSCS may elicit greater muscle activation than either modality alone. The objective of this study is to quantify the torque at the ankle joint generated by tSCS, by FES, and by tSCS + FES. Additionally, ultrasound images will be collected during stimulation to provide a metric of muscle activity. The correlation between ultrasound and torque will be assessed to determine if ultrasound is a useful modality for quantifying tSCS-elicited muscle activity.
Primary Outcome
Ankle joint torque will be collected during stimulation with FES, with tSCS, and with FES + tSCS. We will compare the torque elicited by each simulation case.
Conditions Studied
Interventions
- DEVICE Ultrasound
- DEVICE Functional Electrical Stimulation
- DEVICE Transcutaneous (Non-Invasive) Spinal Cord Stimulation
Study Locations (1)
North Carolina
- Engineering Building III - Raleigh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2025-06-01 |
| Est. Completion | 2026-06-01 |
| Phase | NA |
What NCT07206797 shows while recruiting
NCT07206797 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Neuromodulatory Effects of TSCS and FES in Lower Limbs appearing as the primary indexed condition, and to 3 interventions - of which Ultrasound is the first listed.
NCT07206797 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT07206797 about?
NCT07206797 is a clinical study titled "Ultrasound for Quantifying Muscle Activation Elicited by Spinal Cord Stimulation and Functional Electrical Stimulation". Transcutaneous (non-invasive) spinal cord stimulation (tSCS) has been shown to facilitate volitional motor activity in patients with spinal cord injury. tSCS is known to activate the same neural structures as invasive SCS, meaning it may have the potential for functional restoration without an expen...
What is the current status of trial NCT07206797?
This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2025-06-01. Estimated completion is 2026-06-01.
What conditions does trial NCT07206797 study?
This clinical trial studies the following conditions: Neuromodulatory Effects of TSCS and FES in Lower Limbs.
What interventions are being tested in trial NCT07206797?
The interventions under investigation include: Ultrasound (DEVICE), Functional Electrical Stimulation (DEVICE), Transcutaneous (Non-Invasive) Spinal Cord Stimulation (DEVICE).
Who is sponsoring clinical trial NCT07206797?
This trial is sponsored by North Carolina State University, which has 19 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07206797 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07206797's enrollment target sits among peer trials
30 1593rd of 2000 higher than 299 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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