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NCT07206589 · ClinicalTrials.gov registry record · NA
Minimally Invasive Approaches for the Diagnosis of Barrett's Esophagus and Esophageal Cancer, SOS5C Trial
A NA study, sponsored by Mayo Clinic.
- Not yet
- Registry status
- NA
- Development phase
- 1,010
- Enrollment target
NCT07206589: Clinical Trial NA study, sponsored by Mayo Clinic.
NCT07206589 is a NA study that has not yet begun recruiting, run by Mayo Clinic. The registered enrollment target is 1,010 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07206589, a NA study, has not yet begun recruiting, sponsored by Mayo Clinic.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 1,010 participants
- Enrollment target
Study Summary
This clinical trial studies how well minimally invasive approaches (an artificial intelligence \[AI\] powered risk tool, nurse navigation, and a sponge on a string \[SOS\] test) work in diagnosing patients with Barrett's esophagus (BE) and esophageal cancer. Esophageal cancer has a poor 5-year survival rate when diagnosed after onset of symptoms. While rising, incidence of esophageal cancer remains too low to screen the entire population. BE is a condition in which the cells lining the lower part of the esophagus have changed or been replaced with abnormal cells that could lead to esophageal cancer. Currently, patients are screened for BE based on certain risk factors (reflux, age \> 50 years, White race, family history of esophageal cancer, obesity, male sex, and smoking), followed by endoscopies and surgery for treatment. These standard procedures may result in under-recognition of BE risk due to inaccurate and difficult to use risk assessment tools, high cost, invasiveness, low access to endoscopy, and sub-optimal recognition of abnormal cells during routing endoscopy. An AI powered risk tool that integrates symptoms, health history, and laboratory values from electronic health record data may more accurately assess BE and esophageal cancer risk that manual assessment. The BE-SOS screening test combines a swallowable cell collection device with assessment of DNA, which may more accurately diagnose abnormal cells. Nurse navigation involves trained personnel assisting individuals through the screening process and completing the follow-up diagnostic test if the screening test is positive. Navigators address cultural, social, access, and logistical barriers to screening. Nurse navigation may increase completion rates of diagnostic procedures following a positive screening test. These minimally invasive approaches may enable higher rates of BE screening than currently being accomplished.
Interventions
- OTHER Navigation
- PROCEDURE Endoscopic Procedure
- OTHER Cancer Screening
- OTHER Computer-Assisted Intervention
- BEHAVIORAL Health Risk Assessment
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,010 participants |
| Start Date | 2026-12-01 |
| Est. Completion | 2030-07-31 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07206589
The ClinicalTrials.gov registry entry for NCT07206589 describes a study currently listed as not yet recruiting, categorized as NA. The registered enrollment target is 1,010 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 5 interventions - of which Navigation is the first listed.
NCT07206589 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07206589 about?
NCT07206589 is a clinical study titled "Minimally Invasive Approaches for the Diagnosis of Barrett's Esophagus and Esophageal Cancer, SOS5C Trial". This clinical trial studies how well minimally invasive approaches (an artificial intelligence \[AI\] powered risk tool, nurse navigation, and a sponge on a string \[SOS\] test) work in diagnosing patients with Barrett's esophagus (BE) and esophageal cancer. Esophageal cancer has a poor 5-year survi...
What is the current status of trial NCT07206589?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 1,010 participants. The study started on 2026-12-01. Estimated completion is 2030-07-31.
What interventions are being tested in trial NCT07206589?
The interventions under investigation include: Navigation (OTHER), Endoscopic Procedure (PROCEDURE), Cancer Screening (OTHER), Computer-Assisted Intervention (OTHER), Health Risk Assessment (BEHAVIORAL).
Who is sponsoring clinical trial NCT07206589?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
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