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NCT07184970 · ClinicalTrials.gov registry record

PRISM Study: Prostate Recurrence Detection Using Imaging With PSMA PET/MRI Post-high Intensity Focused Ultrasound

A clinical trial of Prostate Cancer, sponsored by NYU Langone Health.

Recruiting
Registry status
60
Enrollment target
1
Study location

NCT07184970: Recruiting study of Prostate Cancer, sponsored by NYU Langone Health.

NCT07184970 is a study of Prostate Cancer that is actively recruiting participants, run by NYU Langone Health. The registered enrollment target is 60 participants, below the 608-participant average among 735 other Prostate Cancer trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07184970, a study of Prostate Cancer, is actively recruiting participants, sponsored by NYU Langone Health.

RECRUITING
Registry status
60 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to compare the sensitivity of PSMA PET/MRI and standard MRI in detecting focal therapy failure in the prostate one year after High-Intensity Focused Ultrasound (HIFU) treatment. Specifically, the study aims to evaluate whether PSMA PET/MRI offers a higher sensitivity than MRI alone for identifying recurrence or failure in patients undergoing focal therapy.

Primary Outcome

Sensitivity of PSMA PET/MRI for detecting clinically significant prostate cancer at 12 months post HIFU, defined as the portion of patients with clinically significant cancer on the 12-month biopsy (reference standard) who had a positive PSMA PET/MRI.

Conditions Studied

Study Locations (1)

New York

  • NYU Langone Health - New York

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2025-10-08
Est. Completion 2028-10-01
NYU Langone Health

1,164 total trials

What NCT07184970 shows while recruiting

NCT07184970 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 608-participant average among 735 other Prostate Cancer trials with a reported enrollment target (90% lower).

The record links to 1 condition, with Prostate Cancer appearing as the primary indexed condition, and to 0 interventions.

NCT07184970 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT07184970 about?

NCT07184970 is a clinical study titled "PRISM Study: Prostate Recurrence Detection Using Imaging With PSMA PET/MRI Post-high Intensity Focused Ultrasound". The purpose of this study is to compare the sensitivity of PSMA PET/MRI and standard MRI in detecting focal therapy failure in the prostate one year after High-Intensity Focused Ultrasound (HIFU) treatment. Specifically, the study aims to evaluate whether PSMA PET/MRI offers a higher sensitivity tha...

What is the current status of trial NCT07184970?

This trial is currently recruiting. The enrollment target is 60 participants. The study started on 2025-10-08. Estimated completion is 2028-10-01.

What conditions does trial NCT07184970 study?

This clinical trial studies the following conditions: Prostate Cancer.

Who is sponsoring clinical trial NCT07184970?

This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07184970 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Prostate Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT07184970's enrollment target sits among peer trials

60 421st of 735 higher than 293 of 735 other Prostate Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Prostate Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07184970, the US trial registry maintained by the National Library of Medicine. NCT07184970 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.