Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT07182591 · ClinicalTrials.gov registry record · Phase 1

A Study of DS5361b in Participants With Advanced Solid Tumors

A Phase 1 study of Advanced Solid Tumor, sponsored by Daiichi Sankyo.

Recruiting
Registry status
Phase 1
Development phase
192
Enrollment target
7
Study locations

NCT07182591 is a Phase 1 study of Advanced Solid Tumor that is actively recruiting participants, run by Daiichi Sankyo. The registered enrollment target is 192 participants, roughly in line with the 192-participant average among 189 other Advanced Solid Tumor trials with a reported enrollment target. The trial reports 7 study locations across 5 states.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT07182591, a Phase 1 study of Advanced Solid Tumor, is actively recruiting participants, sponsored by Daiichi Sankyo.

RECRUITING
Registry status
Phase 1
Development phase
192 participants
Enrollment target
7
Study locations

Study Summary

This study aims to assess the safety, tolerability, and preliminary efficacy and to determine the MTD of DS5361b in monotherapy and combination with pembrolizumab in participants with advanced or metastatic solid tumors.

Conditions Studied

Advanced Solid Tumor

Interventions

  • DRUG Pembrolizumab
  • DRUG DS5361b

Study Locations (7)

Texas

  • Research Site - Irving
  • Research Site - San Antonio

Other

  • Research Site - Chiba
  • Research Site - Kōtoku

Florida

  • Research Site - Sarasota

Rhode Island

  • Research Site - Providence

Virginia

  • Research Site - Fairfax

Trial Details

FieldValue
Enrollment Target 192 participants
Start Date 2025-10-02
Est. Completion 2030-12-03
Phase Phase 1

Sponsor

Daiichi Sankyo

236 total trials

Interested in This Trial?

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07182591

The ClinicalTrials.gov registry entry for NCT07182591 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 192 participants, a figure that helps gauge the scale of data the investigators plan to collect, roughly in line with the 192-participant average among 189 other Advanced Solid Tumor trials with a reported enrollment target. The listed sponsor is Daiichi Sankyo, which has 236 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Advanced Solid Tumor appearing as the primary indexed condition, and to 2 interventions - of which Pembrolizumab is the first listed.

NCT07182591 reports 7 study locations spanning 5 distinct geographic areas - top geographies include Texas, Other, Florida.

Frequently Asked Questions

What is clinical trial NCT07182591 about?

NCT07182591 is a clinical study titled "A Study of DS5361b in Participants With Advanced Solid Tumors". This study aims to assess the safety, tolerability, and preliminary efficacy and to determine the MTD of DS5361b in monotherapy and combination with pembrolizumab in participants with advanced or metastatic solid tumors.

What is the current status of trial NCT07182591?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 192 participants. The study started on 2025-10-02. Estimated completion is 2030-12-03.

What conditions does trial NCT07182591 study?

This clinical trial studies the following conditions: Advanced Solid Tumor.

What interventions are being tested in trial NCT07182591?

The interventions under investigation include: Pembrolizumab (DRUG), DS5361b (DRUG).

Who is sponsoring clinical trial NCT07182591?

This trial is sponsored by Daiichi Sankyo, which has 236 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07182591 being conducted?

This trial has 7 study locations across Florida, Rhode Island, Texas, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Advanced Solid Tumor

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Explore more on PlainTrial

Advanced Solid Tumor

All registered trials for this condition

Florida

All trials with a study site in Florida

Recruiting now

Find trials open to new participants near you

Rankings

Top sponsors, conditions, and phases

Read our methodology - how this data is sourced, computed, and verified.

Related

Browse all → | Rankings →
Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.