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NCT07175129 · ClinicalTrials.gov registry record · NA

Transverse Tibial Transport for Chronic Limb-Threatening Ischemia (CLTI)

A NA study of Chronic Limb-Threatening Ischemia, sponsored by University Hospitals Cleveland Medical Center.

Recruiting
Registry status
NA
Development phase
10
Enrollment target
1
Study location

NCT07175129 is a NA study of Chronic Limb-Threatening Ischemia that is actively recruiting participants, run by University Hospitals Cleveland Medical Center. The registered enrollment target is 10 participants, below the 184-participant average among 9 other Chronic Limb-Threatening Ischemia trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07175129, a NA study of Chronic Limb-Threatening Ischemia, is actively recruiting participants, sponsored by University Hospitals Cleveland Medical Center.

RECRUITING
Registry status
NA
Development phase
10 participants
Enrollment target
1
Study location

Study Summary

Chronic limb-threatening ischemia (CLTI) is a serious condition that happens when blood flow to the legs or feet is severely reduced. This can lead to constant pain, wounds that don't heal, infections, and in some cases, the need for amputation. Some people with CLTI have such severe artery disease that doctors are unable to restore blood flow using standard treatments like surgery or stents. For these patients, major amputation may be the only remaining option. This study aims to test a new surgical technique called transverse tibial bone transport, which has been shown in some previous small studies to help improve blood flow and promote healing of wounds in the legs and feet. These early studies suggest that the procedure may help wounds heal better and reduce the need for amputation in people with severe circulation problems. This research will help us learn more about how safe and effective this technique is for patients who have no other treatment options other than amputation.

Interventions

  • PROCEDURE Transverse Tibial Bone Transport
  • DEVICE TrueLok Elevate

Study Locations (1)

Ohio

  • University Hospitals Cleveland Medical Center - Cleveland

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2026-01-05
Est. Completion 2027-06
Phase NA

What the Registry Record Tells You About NCT07175129

The ClinicalTrials.gov registry entry for NCT07175129 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 184-participant average among 9 other Chronic Limb-Threatening Ischemia trials with a reported enrollment target (95% lower). The listed sponsor is University Hospitals Cleveland Medical Center, which has 230 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Chronic Limb-Threatening Ischemia appearing as the primary indexed condition, and to 2 interventions - of which Transverse Tibial Bone Transport is the first listed.

NCT07175129 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT07175129 about?

NCT07175129 is a clinical study titled "Transverse Tibial Transport for Chronic Limb-Threatening Ischemia (CLTI)". Chronic limb-threatening ischemia (CLTI) is a serious condition that happens when blood flow to the legs or feet is severely reduced. This can lead to constant pain, wounds that don't heal, infections, and in some cases, the need for amputation. Some people with CLTI have such severe artery disease...

What is the current status of trial NCT07175129?

This trial is currently recruiting. It is a NA study. The enrollment target is 10 participants. The study started on 2026-01-05. Estimated completion is 2027-06.

What conditions does trial NCT07175129 study?

This clinical trial studies the following conditions: Chronic Limb-Threatening Ischemia.

What interventions are being tested in trial NCT07175129?

The interventions under investigation include: Transverse Tibial Bone Transport (PROCEDURE), TrueLok Elevate (DEVICE).

Who is sponsoring clinical trial NCT07175129?

This trial is sponsored by University Hospitals Cleveland Medical Center, which has 230 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07175129 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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