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NCT07158437 · ClinicalTrials.gov registry record · Phase 1
Phase 1 Study of SL-325 in Healthy Volunteers
A Phase 1 study of Healthy Volunteers, sponsored by Shattuck Labs.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 72
- Enrollment target
- 1
- Study location
NCT07158437: Recruiting Phase 1 study of Healthy Volunteers, sponsored by Shattuck Labs.
NCT07158437 is a Phase 1 study of Healthy Volunteers that is actively recruiting participants, run by Shattuck Labs. The registered enrollment target is 72 participants, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07158437, a Phase 1 study of Healthy Volunteers, is actively recruiting participants, sponsored by Shattuck Labs.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 72 participants
- Enrollment target
- 1
- Study location
Study Summary
This first-in-human study is a randomized, double-blind, placebo-controlled, single-ascending dose and multiple-ascending dose study of SL-325 in healthy volunteers.
Primary Outcome
Incidence and severity of treatment-emergent adverse events
Conditions Studied
Interventions
- BIOLOGICAL SL-325
- OTHER Placebo (Normal Saline)
Study Locations (1)
Nebraska
- Celerion - Lincoln
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 72 participants |
| Start Date | 2025-09 |
| Est. Completion | 2026-07 |
| Phase | Phase 1 |
What NCT07158437 shows while recruiting
NCT07158437 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 72 participants, a relatively small participant target, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (85% lower).
The record links to 1 condition, with Healthy Volunteers appearing as the primary indexed condition, and to 2 interventions - of which SL-325 is the first listed.
NCT07158437 reports a single indexed study location in Nebraska.
Frequently Asked Questions
What is clinical trial NCT07158437 about?
NCT07158437 is a clinical study titled "Phase 1 Study of SL-325 in Healthy Volunteers". This first-in-human study is a randomized, double-blind, placebo-controlled, single-ascending dose and multiple-ascending dose study of SL-325 in healthy volunteers.
What is the current status of trial NCT07158437?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 72 participants. The study started on 2025-09. Estimated completion is 2026-07.
What conditions does trial NCT07158437 study?
This clinical trial studies the following conditions: Healthy Volunteers.
What interventions are being tested in trial NCT07158437?
The interventions under investigation include: SL-325 (BIOLOGICAL), Placebo (Normal Saline) (OTHER).
Who is sponsoring clinical trial NCT07158437?
This trial is sponsored by Shattuck Labs, which has 6 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07158437 being conducted?
This trial has 1 study location across Nebraska. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy Volunteers
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07158437's enrollment target sits among peer trials
72 93rd of 283 higher than 190 of 283 other Healthy Volunteers trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy Volunteers trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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