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NCT07120971 · ClinicalTrials.gov registry record · Early Phase 1
Metformin for Premature Infants With Bronchopulmonary Dysplasia
A Early Phase 1 study of Bronchopulmonary Dysplasia (BPD), sponsored by Medical College of Wisconsin.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT07120971 is a Early Phase 1 study of Bronchopulmonary Dysplasia (BPD) that is actively recruiting participants, run by Medical College of Wisconsin. The registered enrollment target is 40 participants, below the 589-participant average among 5 other Bronchopulmonary Dysplasia (BPD) trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07120971, a Early Phase 1 study of Bronchopulmonary Dysplasia (BPD), is actively recruiting participants, sponsored by Medical College of Wisconsin.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
The overall objective of this study is to investigate the role of metformin in decreasing lung injury and promoting lung growth in premature infants. There are two phases to this pilot study. For Phase 0, the goal is to investigate the safety and tolerance of oral metformin in premature who have been diagnosed with bronchopulmonary dysplasia (BPD) at 36-44 weeks gestation. For Phase 1, the goal is to investigate metformin safety and tolerance in extremely premature infants who are 7-30 days old who have an increased risk of BPD. The main questions it aims to answer are: * how well do older premature infants tolerate metformin? * how well do younger premature infants tolerate metformin?
Conditions Studied
Interventions
- DRUG Metformin (open-label)
Study Locations (1)
Wisconsin
- Children's Wisconsin - Milwaukee
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2025-12-19 |
| Est. Completion | 2030-09-01 |
| Phase | Early Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07120971
The ClinicalTrials.gov registry entry for NCT07120971 describes a study currently listed as recruiting, categorized as Early Phase 1. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 589-participant average among 5 other Bronchopulmonary Dysplasia (BPD) trials with a reported enrollment target (93% lower). The listed sponsor is Medical College of Wisconsin, which has 447 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Bronchopulmonary Dysplasia (BPD) appearing as the primary indexed condition, and to 1 intervention - of which Metformin (open-label) is the first listed.
NCT07120971 reports 1 study location spanning 1 distinct geographic area - top geographies include Wisconsin.
Frequently Asked Questions
What is clinical trial NCT07120971 about?
NCT07120971 is a clinical study titled "Metformin for Premature Infants With Bronchopulmonary Dysplasia". The overall objective of this study is to investigate the role of metformin in decreasing lung injury and promoting lung growth in premature infants. There are two phases to this pilot study. For Phase 0, the goal is to investigate the safety and tolerance of oral metformin in premature who have bee...
What is the current status of trial NCT07120971?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 40 participants. The study started on 2025-12-19. Estimated completion is 2030-09-01.
What conditions does trial NCT07120971 study?
This clinical trial studies the following conditions: Bronchopulmonary Dysplasia (BPD).
What interventions are being tested in trial NCT07120971?
The interventions under investigation include: Metformin (open-label) (DRUG).
Who is sponsoring clinical trial NCT07120971?
This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07120971 being conducted?
This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.