Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
Study to Evaluate the Safety, Pharmacology and Efficacy of WIN378 in Adults With Moderate or Severe Asthma
NCT07120503 · View on ClinicalTrials.gov ↗
Study Summary
This study is trying to identify the right dose of a long-acting medicine called WIN378 for people with moderate or severe asthma. WIN378 blocks the action of a protein called TSLP which causes inflammation in the lung and may contribute to your asthma control and symptoms. The study will test how doses of WIN378 are handled by your body (pharmacokinetics) and assess the safety of the medicine and will assess markers of asthma inflammation in your breath and in your blood, lung function and asthma control (pharmacodynamics).
Conditions Studied
Interventions
- DRUG Placebo
- DRUG WIN378
Study Locations (20)
Texas
- WB Contracted Clinical Research Site — Austin
- WB Contracted Clinical Research Site — El Paso
- WB Contracted Clinical Research Site — McKinney
- WB Contracted Clinical Research Site — San Antonio
- WB Contracted Clinical Research Site — Tyler
California
- WB Contracted Clinical Research Site — Los Angeles
- WB Contracted Clinical Research Site — San Jose
Florida
- WB Contracted Clinical Research Site — Melbourne
- WB Contracted Clinical Research Site — Miami
South Carolina
- WB Contracted Clinical Research Site — Charleston
- WB Contracted Clinical Research Site — Spartanburg
Buenos Aires F.D.
- WB Contracted Clinical Research Site — Buenos Aires
- WB Contracted Clinical Research Site — Buenos Aires
Maryland
- WB Contracted Clinical Research Site — White Marsh
Minnesota
- WB Contracted Clinical Research Site — Richfield
Missouri
- WB Contracted Clinical Research Site — St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 136 participants |
| Start Date | 2025-07-24 |
| Est. Completion | 2027-10 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07120503
The ClinicalTrials.gov registry entry for NCT07120503 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 136 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Windward Bio, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Asthma (Diagnosis) appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT07120503 reports 20 study locations spanning 12 distinct geographic areas — top geographies include Texas, California, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT07120503 about?
NCT07120503 is a clinical study titled "Study to Evaluate the Safety, Pharmacology and Efficacy of WIN378 in Adults With Moderate or Severe Asthma". This study is trying to identify the right dose of a long-acting medicine called WIN378 for people with moderate or severe asthma. WIN378 blocks the action of a protein called TSLP which causes inflammation in the lung and may contribute to your asthma control and symptoms. The study will test how d...
What is the current status of trial NCT07120503?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 136 participants. The study started on 2025-07-24. Estimated completion is 2027-10.
What conditions does trial NCT07120503 study?
This clinical trial studies the following conditions: Asthma (Diagnosis). These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT07120503?
The interventions under investigation include: Placebo (DRUG), WIN378 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT07120503?
This trial is sponsored by Windward Bio, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT07120503 being conducted?
This trial has 20 study locations across California, Florida, Maryland, Minnesota, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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