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NCT07105228 · ClinicalTrials.gov registry record

Incidence of Retinal Vasculitis Among Patients Receiving Aflibercept: A US Real-World Evidence Study

A clinical trial, sponsored by Regeneron Pharmaceuticals.

Completed
Registry status
290,000
Enrollment target

NCT07105228 is a clinical trial that has completed, run by Regeneron Pharmaceuticals. The registered enrollment target is 290,000 participants.

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The verdict

NCT07105228 has completed, sponsored by Regeneron Pharmaceuticals.

COMPLETED
Registry status
290,000 participants
Enrollment target

Study Summary

This study will describe and estimate the incidence of Retinal Vasculitis (RV) events among patients and patient eyes receiving aflibercept intravitreal (IVT) (Eylea®, aflibercept 2mg) therapy in US clinical practice. The main objective is to describe demographic and clinical characteristics of patients receiving aflibercept 2mg injections, to estimate the incidence of RV and RV plus Intraocular Inflammation (IOI) following aflibercept 2mg injections and to describe characteristics of RV cases.

Interventions

  • DRUG aflibercept 2mg

Trial Details

FieldValue
Enrollment Target 290,000 participants
Start Date 2025-07-15
Est. Completion 2025-09-15

Sponsor

Regeneron Pharmaceuticals

280 total trials

What the Registry Record Tells You About NCT07105228

The ClinicalTrials.gov registry entry for NCT07105228 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 290,000 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Regeneron Pharmaceuticals, which has 280 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which aflibercept 2mg is the first listed.

NCT07105228 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07105228 about?

NCT07105228 is a clinical study titled "Incidence of Retinal Vasculitis Among Patients Receiving Aflibercept: A US Real-World Evidence Study". This study will describe and estimate the incidence of Retinal Vasculitis (RV) events among patients and patient eyes receiving aflibercept intravitreal (IVT) (Eylea®, aflibercept 2mg) therapy in US clinical practice. The main objective is to describe demographic and clinical characteristics of pat...

What is the current status of trial NCT07105228?

This trial is currently completed. The enrollment target is 290,000 participants. The study started on 2025-07-15. Estimated completion is 2025-09-15.

What interventions are being tested in trial NCT07105228?

The interventions under investigation include: aflibercept 2mg (DRUG).

Who is sponsoring clinical trial NCT07105228?

This trial is sponsored by Regeneron Pharmaceuticals, which has 280 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.