Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07104279 · ClinicalTrials.gov registry record
Z1 Hip System: Post-Market Clinical Follow Up Study
A clinical trial of Hip Osteoarthritis and Avascular Necrosis of the Femoral Head, sponsored by Zimmer Biomet.
- Recruiting
- Registry status
- 150
- Enrollment target
- 2
- Study locations
NCT07104279: Recruiting study of Hip Osteoarthritis and Avascular Necrosis of the Femoral Head, sponsored by Zimmer Biomet.
NCT07104279 is a study of Hip Osteoarthritis and Avascular Necrosis of the Femoral Head that is actively recruiting participants, run by Zimmer Biomet. The registered enrollment target is 150 participants, below the 391-participant average among 11 other Hip Osteoarthritis trials with a reported enrollment target (62% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07104279, a study of Hip Osteoarthritis and Avascular Necrosis of the Femoral Head, is actively recruiting participants, sponsored by Zimmer Biomet.
- RECRUITING
- Registry status
- 150 participants
- Enrollment target
- 2
- Study locations
Study Summary
The objectives of this study are to confirm the early to mid-term safety, performance, and clinical benefits of the Z1 Femoral Hip System in hemi-hip arthroplasty and primary total hip arthroplasty. The primary objective of this post market clinical follow-up (PMCF) study is the assessment of safety by recording and analyzing the survival of the implant system at 2 years post-implantation. Safety will also be established by recording the incidence and frequency of revisions, complications, and adverse events. Relation of the events to implant, instrumentation, and/or procedure should be specified. The secondary objective is the assessment of functional performance and clinical benefits of the Z1 Femoral Hip System demonstrated by recording patient-reported clinical outcomes measures (PROMs).
Primary Outcome
The primary endpoint is defined by the survival of the implant system at 2 years, which is based on the absence of removal of the study device and will be evaluated using a one-sample proportion as well as using the Kaplan Meier method. The safety of the system will additionally be assessed by monitoring the frequency and incidence of adverse events, including relation to implant, instrumentation, and/or procedure. Cohort 1
Conditions Studied
Interventions
- DEVICE Z1 Femoral Hip System
Study Locations (2)
North Carolina
- OrthoCarolina/OrthoCarolina Research Institute - Charlotte
Oregon
- Orthopedic & Fracture Specialists - Portland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2025-10-13 |
| Est. Completion | 2031-08 |
What NCT07104279 shows while recruiting
NCT07104279 is an observational study that tracks outcomes without assigning an intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, below the 391-participant average among 11 other Hip Osteoarthritis trials with a reported enrollment target (62% lower).
The record links to 3 conditions, with Hip Osteoarthritis appearing as the primary indexed condition, and to 1 intervention - of which Z1 Femoral Hip System is the first listed.
NCT07104279 reports a single indexed study location in North Carolina, Oregon.
Frequently Asked Questions
What is clinical trial NCT07104279 about?
NCT07104279 is a clinical study titled "Z1 Hip System: Post-Market Clinical Follow Up Study". The objectives of this study are to confirm the early to mid-term safety, performance, and clinical benefits of the Z1 Femoral Hip System in hemi-hip arthroplasty and primary total hip arthroplasty. The primary objective of this post market clinical follow-up (PMCF) study is the assessment of safet...
What is the current status of trial NCT07104279?
This trial is currently recruiting. The enrollment target is 150 participants. The study started on 2025-10-13. Estimated completion is 2031-08.
What conditions does trial NCT07104279 study?
This clinical trial studies the following conditions: Hip Osteoarthritis, Avascular Necrosis of the Femoral Head, Acute Traumatic Fracture of the Femoral Head or Neck.
What interventions are being tested in trial NCT07104279?
The interventions under investigation include: Z1 Femoral Hip System (DEVICE).
Who is sponsoring clinical trial NCT07104279?
This trial is sponsored by Zimmer Biomet, which has 115 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07104279 being conducted?
This trial has 2 study locations across North Carolina, Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hip Osteoarthritis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07104279's enrollment target sits among peer trials
150 6th of 11 higher than 6 of 11 other Hip Osteoarthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hip Osteoarthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Restoration Anatomic Acetabular Shell Revision Study
RECRUITING · NA
-
General vs Spinal in Total Joint Arthroplasty (TJA)
RECRUITING · NA
-
Platelet Rich Plasma Versus Corticosteroids in Hip Osteoarthritis Pain
RECRUITING · Phase 4
-
The Pericapsular Nerve Block in Total Hip Arthroplasty
RECRUITING · Phase 4
-
Return to Golf After Orthopaedic Surgery
RECRUITING
-
Positioning for Hip Arthroscopic Surgery to Reduce Postoperative Numbness
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00412594 · 150 participants · Phase 2
Cladribine and Rituximab in Treating Patients With Hairy Cell Leukemia
- NCT01484730 · 150 participants
A Pilot Study to Evaluate Multi-Spectral and Laser Speckle Imaging and Multiphoton Microscopy During Vascular Occlusion
- NCT01985919 · 150 participants
Protocol for Facilitating the Acquisition of Research Bone Marrow and Blood Samples
- NCT02016248 · 150 participants · NA
SBRT Boost for Unfavorable Prostate Cancer'
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI