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NCT07091630 · ClinicalTrials.gov registry record · Phase 3

A Study to Assess the Efficacy and Safety of Empasiprubart in Adults With CIDP

A Phase 3 study of Chronic Inflammatory Demyelinating Polyneuropathy and CIDP, sponsored by argenx.

Recruiting
Registry status
Phase 3
Development phase
160
Enrollment target
19
Study locations

NCT07091630 is a Phase 3 study of Chronic Inflammatory Demyelinating Polyneuropathy and CIDP that is actively recruiting participants, run by argenx. The registered enrollment target is 160 participants, above the 146-participant average among 11 other Chronic Inflammatory Demyelinating Polyneuropathy trials with a reported enrollment target (10% higher). The trial reports 19 study locations across 6 states.

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The verdict

NCT07091630, a Phase 3 study of Chronic Inflammatory Demyelinating Polyneuropathy and CIDP, is actively recruiting participants, sponsored by argenx.

RECRUITING
Registry status
Phase 3
Development phase
160 participants
Enrollment target
19
Study locations

Study Summary

The main purpose of this study is to demonstrate the efficacy and safety of empasiprubart in adults with CIDP. The study consists of a part A where participants will either receive empasiprubart or placebo for 24 weeks (6 months). Following part A, participants will enter part B in which all participants will receive empasiprubart for 96 weeks (24 months). More information can be found here: https://clinicaltrials.argenx.com/emnergize

Interventions

  • BIOLOGICAL Empasiprubart IV
  • OTHER Placebo IV

Study Locations (19)

Other

  • Peking University First Hospital - Changqiao Campus - Beijing
  • Nanfang Hospital Southern Medical University - Guangzhou
  • High Technology Hospital MedCenter Ltd - Batumi
  • First Medical Clinic LLC - Batumi
  • Petre Sarajishvili Institute of Neurology - Tbilisi
  • Aleksandre Aladashvili Clinic - Tbilisi
  • Curatio JSC - Tbilisi
  • LTD New Hospitals - Tbilisi
  • Geo Hospitals - Tbilisi
  • Jo Ann Medical Center - Tbilisi
  • Southern TOHOKU Medical Clinic - Kōriyama
  • Seoul National University Hospital - Seoul
  • Korea University Guro Hospital - Seoul

Texas

  • National Neuromuscular Research Institute - Austin
  • NeuroCarePlus - Houston

Colorado

  • Colorado Springs Neurological Associates - Colorado Springs

District of Columbia

  • Medstar Health Research Institute - Washington D.C.

Florida

  • Gables Neurology - Miami

Louisiana

  • Paradigm Health System - Slidell

Trial Details

FieldValue
Enrollment Target 160 participants
Start Date 2025-09-16
Est. Completion 2031-01-23
Phase Phase 3

Sponsor

argenx

49 total trials

What the Registry Record Tells You About NCT07091630

The ClinicalTrials.gov registry entry for NCT07091630 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 160 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 146-participant average among 11 other Chronic Inflammatory Demyelinating Polyneuropathy trials with a reported enrollment target (10% higher). The listed sponsor is argenx, which has 49 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Chronic Inflammatory Demyelinating Polyneuropathy appearing as the primary indexed condition, and to 2 interventions - of which Empasiprubart IV is the first listed.

NCT07091630 reports 19 study locations spanning 6 distinct geographic areas - top geographies include Other, Texas, Colorado.

Frequently Asked Questions

What is clinical trial NCT07091630 about?

NCT07091630 is a clinical study titled "A Study to Assess the Efficacy and Safety of Empasiprubart in Adults With CIDP". The main purpose of this study is to demonstrate the efficacy and safety of empasiprubart in adults with CIDP. The study consists of a part A where participants will either receive empasiprubart or placebo for 24 weeks (6 months). Following part A, participants will enter part B in which all partici...

What is the current status of trial NCT07091630?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 160 participants. The study started on 2025-09-16. Estimated completion is 2031-01-23.

What conditions does trial NCT07091630 study?

This clinical trial studies the following conditions: Chronic Inflammatory Demyelinating Polyneuropathy, CIDP, Chronic Inflammatory Demyelinating Polyradiculoneuropathy.

What interventions are being tested in trial NCT07091630?

The interventions under investigation include: Empasiprubart IV (BIOLOGICAL), Placebo IV (OTHER).

Who is sponsoring clinical trial NCT07091630?

This trial is sponsored by argenx, which has 49 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07091630 being conducted?

This trial has 19 study locations across Colorado, District of Columbia, Florida, Louisiana, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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