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NCT06290141 · ClinicalTrials.gov registry record · Phase 3

A Study to Test the Efficacy and Safety of Riliprubart Against the Usual Treatment of Intravenous Immunoglobulin (IVIg) in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

A Phase 3 study of Chronic Inflammatory Demyelinating Polyneuropathy, sponsored by Sanofi.

Recruiting
Registry status
Phase 3
Development phase
160
Enrollment target
20
Study locations

NCT06290141 is a Phase 3 study of Chronic Inflammatory Demyelinating Polyneuropathy that is actively recruiting participants, run by Sanofi. The registered enrollment target is 160 participants, above the 146-participant average among 11 other Chronic Inflammatory Demyelinating Polyneuropathy trials with a reported enrollment target (10% higher). The trial reports 20 study locations across 14 states.

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The verdict

NCT06290141, a Phase 3 study of Chronic Inflammatory Demyelinating Polyneuropathy, is actively recruiting participants, sponsored by Sanofi.

RECRUITING
Registry status
Phase 3
Development phase
160 participants
Enrollment target
20
Study locations

Study Summary

The purpose of the study is to evaluate efficacy of riliprubart compared to IVIg in adult participants with CIDP who are receiving maintenance treatment with IVIg. The study duration will be for a maximum of 109 weeks including screening, treatment phases, and follow-up.

Interventions

  • DRUG Placebo
  • DRUG riliprubart
  • DRUG IVIg

Study Locations (20)

New York

  • Dent Neurologic Institute - Amherst- Site Number : 8400039 - Amherst
  • Hospital for Special Surgery- Site Number : 8400041 - New York
  • Columbia University Irving Medical Center- Site Number : 8400003 - New York

California

  • Keck School of Medicine of University of Southern California- Site Number : 8400002 - Los Angeles
  • University of California Irvine Medical Center- Site Number : 8400007 - Orange

Florida

  • AdventHealth Orlando- Site Number : 8400006 - Orlando
  • AdventHealth Site Number : 8400006 - Orlando

Michigan

  • Henry Ford Hospital- Site Number : 8400025 - Detroit
  • Michigan State University- Site Number : 8400038 - East Lansing

Ohio

  • University of Cincinnati Medical Center- Site Number : 8400020 - Cincinnati
  • University Hospitals Cleveland Medical Center- Site Number : 8400033 - Cleveland

Alabama

  • Alabama Neurology Associates- Site Number : 8400019 - Homewood

Arizona

  • Honor Health Scottsdale Osborn Medical Center- Site Number : 8400014 - Scottsdale

Connecticut

  • Yale University School of Medicine- Site Number : 8400018 - New Haven

Trial Details

FieldValue
Enrollment Target 160 participants
Start Date 2024-08-21
Est. Completion 2029-01-12
Phase Phase 3

Sponsor

Sanofi

713 total trials

What the Registry Record Tells You About NCT06290141

The ClinicalTrials.gov registry entry for NCT06290141 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 160 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 146-participant average among 11 other Chronic Inflammatory Demyelinating Polyneuropathy trials with a reported enrollment target (10% higher). The listed sponsor is Sanofi, which has 713 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Chronic Inflammatory Demyelinating Polyneuropathy appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.

NCT06290141 reports 20 study locations spanning 14 distinct geographic areas - top geographies include New York, California, Florida.

Frequently Asked Questions

What is clinical trial NCT06290141 about?

NCT06290141 is a clinical study titled "A Study to Test the Efficacy and Safety of Riliprubart Against the Usual Treatment of Intravenous Immunoglobulin (IVIg) in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)". The purpose of the study is to evaluate efficacy of riliprubart compared to IVIg in adult participants with CIDP who are receiving maintenance treatment with IVIg. The study duration will be for a maximum of 109 weeks including screening, treatment phases, and follow-up.

What is the current status of trial NCT06290141?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 160 participants. The study started on 2024-08-21. Estimated completion is 2029-01-12.

What conditions does trial NCT06290141 study?

This clinical trial studies the following conditions: Chronic Inflammatory Demyelinating Polyneuropathy.

What interventions are being tested in trial NCT06290141?

The interventions under investigation include: Placebo (DRUG), riliprubart (DRUG), IVIg (DRUG).

Who is sponsoring clinical trial NCT06290141?

This trial is sponsored by Sanofi, which has 713 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06290141 being conducted?

This trial has 20 study locations across Alabama, Arizona, California, Connecticut, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.