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RECRUITING Phase 3

A Study to Test the Efficacy and Safety of Riliprubart Against the Usual Treatment of Intravenous Immunoglobulin (IVIg) in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

NCT06290141 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of the study is to evaluate efficacy of riliprubart compared to IVIg in adult participants with CIDP who are receiving maintenance treatment with IVIg. The study duration will be for a maximum of 109 weeks including screening, treatment phases, and follow-up.

Interventions

  • DRUG Placebo
  • DRUG riliprubart
  • DRUG IVIg

Study Locations (20)

New York

  • Dent Neurologic Institute - Amherst- Site Number : 8400039 — Amherst
  • Hospital for Special Surgery- Site Number : 8400041 — New York
  • Columbia University Irving Medical Center- Site Number : 8400003 — New York

California

  • Keck School of Medicine of University of Southern California- Site Number : 8400002 — Los Angeles
  • University of California Irvine Medical Center- Site Number : 8400007 — Orange

Florida

  • AdventHealth Orlando- Site Number : 8400006 — Orlando
  • AdventHealth Site Number : 8400006 — Orlando

Michigan

  • Henry Ford Hospital- Site Number : 8400025 — Detroit
  • Michigan State University- Site Number : 8400038 — East Lansing

Ohio

  • University of Cincinnati Medical Center- Site Number : 8400020 — Cincinnati
  • University Hospitals Cleveland Medical Center- Site Number : 8400033 — Cleveland

Alabama

  • Alabama Neurology Associates- Site Number : 8400019 — Homewood

Arizona

  • Honor Health Scottsdale Osborn Medical Center- Site Number : 8400014 — Scottsdale

Connecticut

  • Yale University School of Medicine- Site Number : 8400018 — New Haven

Trial Details

FieldValue
Enrollment Target 160 participants
Start Date 2024-08-21
Est. Completion 2029-01-12
Phase Phase 3

Sponsor

Sanofi

275 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06290141

The ClinicalTrials.gov registry entry for NCT06290141 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 160 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Sanofi, which has 275 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Chronic Inflammatory Demyelinating Polyneuropathy appearing as the primary indexed condition, and to 3 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06290141 reports 20 study locations spanning 14 distinct geographic areas — top geographies include New York, California, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06290141 about?

NCT06290141 is a clinical study titled "A Study to Test the Efficacy and Safety of Riliprubart Against the Usual Treatment of Intravenous Immunoglobulin (IVIg) in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)". The purpose of the study is to evaluate efficacy of riliprubart compared to IVIg in adult participants with CIDP who are receiving maintenance treatment with IVIg. The study duration will be for a maximum of 109 weeks including screening, treatment phases, and follow-up.

What is the current status of trial NCT06290141?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 160 participants. The study started on 2024-08-21. Estimated completion is 2029-01-12.

What conditions does trial NCT06290141 study?

This clinical trial studies the following conditions: Chronic Inflammatory Demyelinating Polyneuropathy. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06290141?

The interventions under investigation include: Placebo (DRUG), riliprubart (DRUG), IVIg (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06290141?

This trial is sponsored by Sanofi, which has 275 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06290141 being conducted?

This trial has 20 study locations across Alabama, Arizona, California, Connecticut, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial