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NCT07091448 · ClinicalTrials.gov registry record · Phase 4

Biotivity A-C Membrane Socket Preservation Study

A Phase 4 study, sponsored by University of Maryland, Baltimore.

Not yet
Registry status
Phase 4
Development phase
12
Enrollment target

NCT07091448 is a Phase 4 study that has not yet begun recruiting, run by University of Maryland, Baltimore. The registered enrollment target is 12 participants.

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The verdict

NCT07091448, a Phase 4 study, has not yet begun recruiting, sponsored by University of Maryland, Baltimore.

NOT YET RECRUITING
Registry status
Phase 4
Development phase
12 participants
Enrollment target

Study Summary

This is a prospective, randomized controlled pilot clinical trial evaluating the efficacy of a human placental-derived amnion chorion membrane (Biotivity™ A/C Plus Membrane) versus a conventional collagen membrane in alveolar ridge preservation (ARP) following atraumatic extraction of single posterior teeth. A total of 12 subjects will be enrolled at the University of Maryland School of Dentistry. The study aims to assess both soft tissue wound healing and hard/soft tissue dimensional changes over a 5-month period prior to dental implant placement. Throughout the approximately 6-month study duration, participants will undergo oral exams, x-rays, surgical procedures, and follow-up visits. All participants will undergo routine tooth extraction, bone graft material and barrier placement, and dental implant placement. Participation in the study is voluntary, and the alternative is to continue routine dental care. Risks include minor discomfort from procedures such as tooth extraction and implant placement. The major benefit of participation in the study is the preservation of jaw dimensions following extraction, which will simplify the placement of a dental implant.

Interventions

  • DEVICE Amnion chorion membrane
  • DEVICE Collagen membrane

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2026-04-01
Est. Completion 2028-10-31
Phase Phase 4

Sponsor

University of Maryland, Baltimore

560 total trials

What the Registry Record Tells You About NCT07091448

The ClinicalTrials.gov registry entry for NCT07091448 describes a study currently listed as not yet recruiting, categorized as Phase 4. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Maryland, Baltimore, which has 560 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Amnion chorion membrane is the first listed.

NCT07091448 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07091448 about?

NCT07091448 is a clinical study titled "Biotivity A-C Membrane Socket Preservation Study". This is a prospective, randomized controlled pilot clinical trial evaluating the efficacy of a human placental-derived amnion chorion membrane (Biotivity™ A/C Plus Membrane) versus a conventional collagen membrane in alveolar ridge preservation (ARP) following atraumatic extraction of single posteri...

What is the current status of trial NCT07091448?

This trial is currently not yet recruiting. It is a Phase 4 study. The enrollment target is 12 participants. The study started on 2026-04-01. Estimated completion is 2028-10-31.

What interventions are being tested in trial NCT07091448?

The interventions under investigation include: Amnion chorion membrane (DEVICE), Collagen membrane (DEVICE).

Who is sponsoring clinical trial NCT07091448?

This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.