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NCT07086833 · ClinicalTrials.gov registry record · NA
The Food Environment, Microbial Cysteine Metabolism, and Cancer Disparities
A NA study of Colorectal Cancer and Diet Modification, sponsored by Purdue University.
- Recruiting
- Registry status
- NA
- Development phase
- 40
- Enrollment target
- 2
- Study locations
NCT07086833: Recruiting NA study of Colorectal Cancer and Diet Modification, sponsored by Purdue University.
NCT07086833 is a NA study of Colorectal Cancer and Diet Modification that is actively recruiting participants, run by Purdue University. The registered enrollment target is 40 participants, below the 1,545-participant average among 381 other Colorectal Cancer trials with a reported enrollment target (97% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07086833, a NA study of Colorectal Cancer and Diet Modification, is actively recruiting participants, sponsored by Purdue University.
- RECRUITING
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
- 2
- Study locations
Study Summary
The goal of this clinical trial is to learn if changing cysteine levels in the diet can influence how the body processes cysteine in Black and White individuals aged 45-75 with a history of non-cancerous polyps. The main questions it aims to answer are: * At the beginning of the study, do Black participants have higher levels of cortisol (a stress hormone) and compounds made from cysteine in their blood when compared to White participants? * Does eating less cysteine lower the body's natural cysteine activity and lead to less gut bacteria that break down cysteine? * Does eating less cysteine lead to less inflammation in the gut and lower levels of markers of inflammation in the blood? Research will compare a high cysteine diet and a low cysteine diet, and each participant will eat both diets. Participants will be in the study for 11 weeks and 2 days. Over the course of the study, participants will: * Eat a high cysteine diet for 3 weeks, and a low cysteine diet for 3 weeks * Eat a moderate cysteine diet for 1 week before each study diet * Complete surveys * Provide blood, stool, and saliva samples * Maintain food logs
Primary Outcome
Fecal calprotectin, a marker of intestinal inflammation, will be measured from 100 mg of stool collected at the respective timeframe using a CALPRO Calprotectin ELISA test.
Conditions Studied
Interventions
- OTHER Low Cysteine Diet
- OTHER High Cysteine Diet
Study Locations (2)
Indiana
- University Hospital Clinical Research Center - Indianapolis
- Purdue Clinical Research Center - West Lafayette
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2025-07-30 |
| Est. Completion | 2027-08-01 |
| Phase | NA |
What NCT07086833 shows while recruiting
NCT07086833 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 1,545-participant average among 381 other Colorectal Cancer trials with a reported enrollment target (97% lower).
The record links to 6 conditions, with Colorectal Cancer appearing as the primary indexed condition, and to 2 interventions - of which Low Cysteine Diet is the first listed.
NCT07086833 reports a single indexed study location in Indiana.
Frequently Asked Questions
What is clinical trial NCT07086833 about?
NCT07086833 is a clinical study titled "The Food Environment, Microbial Cysteine Metabolism, and Cancer Disparities". The goal of this clinical trial is to learn if changing cysteine levels in the diet can influence how the body processes cysteine in Black and White individuals aged 45-75 with a history of non-cancerous polyps. The main questions it aims to answer are: * At the beginning of the study, do Black par...
What is the current status of trial NCT07086833?
This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2025-07-30. Estimated completion is 2027-08-01.
What conditions does trial NCT07086833 study?
This clinical trial studies the following conditions: Colorectal Cancer, Diet Modification, Cancer Prevention, Dietary Intervention, Colorectal Cancer Prevention.
What interventions are being tested in trial NCT07086833?
The interventions under investigation include: Low Cysteine Diet (OTHER), High Cysteine Diet (OTHER).
Who is sponsoring clinical trial NCT07086833?
This trial is sponsored by Purdue University, which has 141 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07086833 being conducted?
This trial has 2 study locations across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Colorectal Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07086833's enrollment target sits among peer trials
40 298th of 381 higher than 76 of 381 other Colorectal Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Colorectal Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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