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NCT07086079 · ClinicalTrials.gov registry record · Phase 1
A Study of Doravirine/Islatravir in Healthy Lactating Females (MK-8591A-061)
A Phase 1 study, sponsored by Merck Sharp & Dohme.
- Completed
- Registry status
- Phase 1
- Development phase
- 12
- Enrollment target
NCT07086079: Completed Phase 1 study, sponsored by Merck Sharp & Dohme.
NCT07086079 is a Phase 1 study that has completed, run by Merck Sharp & Dohme. The registered enrollment target is 12 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07086079, a Phase 1 study, has completed, sponsored by Merck Sharp & Dohme.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 12 participants
- Enrollment target
Study Summary
The goal of this study is to learn what happens to doravirine (DOR) and islatravir (ISL) in a healthy lactating female's body over time. Researchers want to learn if DOR and ISL are in breast milk.
Primary Outcome
Breast milk samples will be collected to determine the Ae0-24hrs after administration of DOR.
Interventions
- DRUG DOR/ISL
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2025-09-26 |
| Est. Completion | 2026-02-04 |
| Phase | Phase 1 |
What the finished NCT07086079 record still lists
NCT07086079 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (80% lower).
The record links to 0 conditions, and to 1 intervention - of which DOR/ISL is the first listed.
NCT07086079 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07086079 about?
NCT07086079 is a clinical study titled "A Study of Doravirine/Islatravir in Healthy Lactating Females (MK-8591A-061)". The goal of this study is to learn what happens to doravirine (DOR) and islatravir (ISL) in a healthy lactating female's body over time. Researchers want to learn if DOR and ISL are in breast milk.
What is the current status of trial NCT07086079?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2025-09-26. Estimated completion is 2026-02-04.
What interventions are being tested in trial NCT07086079?
The interventions under investigation include: DOR/ISL (DRUG).
Who is sponsoring clinical trial NCT07086079?
This trial is sponsored by Merck Sharp & Dohme, which has 558 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07086079's enrollment target sits among peer trials
12 1852nd of 2000 higher than 90 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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