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NCT07084441 · ClinicalTrials.gov registry record · Phase 4
Comparison of Outcomes of Management of Bowel Obstruction
A Phase 4 study of Adhesive Small Bowel Obstruction, sponsored by University of Washington.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 550
- Enrollment target
- 3
- Study locations
NCT07084441: Recruiting Phase 4 study of Adhesive Small Bowel Obstruction, sponsored by University of Washington.
NCT07084441 is a Phase 4 study of Adhesive Small Bowel Obstruction that is actively recruiting participants, run by University of Washington. The registered enrollment target is 550 participants, roughly in line with the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target. The trial reports 3 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07084441, a Phase 4 study of Adhesive Small Bowel Obstruction, is actively recruiting participants, sponsored by University of Washington.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 550 participants
- Enrollment target
- 3
- Study locations
Study Summary
The Comparison of Outcomes of Management of Bowel Obstruction (COMBO) trial is a patient-level randomized trial of a short course of dexamethasone + supportive care vs supportive care alone for patients with adhesion-related small bowel obstruction (aSBO). The goal of the COMBO trial is to answer the question: Can Dexamethasone increases the proportion of patients with resolution of aSBO with non-operative management (without complication) based on an established minimal important clinical difference.
Primary Outcome
The primary outcome is the resolution of aSBO, defined as the absence of obstruction symptoms, in patients receiving dexamethasone + supportive care compared to those receiving supportive care alone
Conditions Studied
Interventions
- OTHER Supportive Care
- DRUG Dexamethasone
Study Locations (3)
Washington
- Harborview Medical Center - Seattle
- UW Medical Center - Northwest - Seattle
- University of Washington Medical Center Montlake - Seattle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 550 participants |
| Start Date | 2026-02 |
| Est. Completion | 2030-12 |
| Phase | Phase 4 |
What NCT07084441 shows while recruiting
NCT07084441 is an interventional study that assigns participants to a tested intervention. The registered 550 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target.
The record links to 1 condition, with Adhesive Small Bowel Obstruction appearing as the primary indexed condition, and to 2 interventions - of which Supportive Care is the first listed.
NCT07084441 reports a single indexed study location in Washington.
Frequently Asked Questions
What is clinical trial NCT07084441 about?
NCT07084441 is a clinical study titled "Comparison of Outcomes of Management of Bowel Obstruction". The Comparison of Outcomes of Management of Bowel Obstruction (COMBO) trial is a patient-level randomized trial of a short course of dexamethasone + supportive care vs supportive care alone for patients with adhesion-related small bowel obstruction (aSBO). The goal of the COMBO trial is to answer th...
What is the current status of trial NCT07084441?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 550 participants. The study started on 2026-02. Estimated completion is 2030-12.
What conditions does trial NCT07084441 study?
This clinical trial studies the following conditions: Adhesive Small Bowel Obstruction.
What interventions are being tested in trial NCT07084441?
The interventions under investigation include: Supportive Care (OTHER), Dexamethasone (DRUG).
Who is sponsoring clinical trial NCT07084441?
This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07084441 being conducted?
This trial has 3 study locations across Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Adhesive Small Bowel Obstruction
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07084441's enrollment target sits among peer trials
550 152nd of 2000 higher than 1,849 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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