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NCT07050173 · ClinicalTrials.gov registry record · Phase 1

Monitoring Patients With Repetitive Head Impact With Gamma-glutamylcysteine Supplementation

A Phase 1 study of Repetitive Head Impacts, sponsored by Pravat Mandal.

Recruiting
Registry status
Phase 1
Development phase
30
Enrollment target
1
Study location

NCT07050173 is a Phase 1 study of Repetitive Head Impacts that is actively recruiting participants, run by Pravat Mandal. The registered enrollment target is 30 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT07050173, a Phase 1 study of Repetitive Head Impacts, is actively recruiting participants, sponsored by Pravat Mandal.

RECRUITING
Registry status
Phase 1
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical trial is to test whether the gamma - glutamylcystiene (GGC) oral supplement can reach the brain and subsequently increase antioxidant glutathione (GSH) level in people with repetitive head impact (RHI). This will reduce the oxidative stress related injury in people with RHI.This unique study's main objective is to test the: 1. Change in GSH in brain and blood levels through GGC supplementation. 2. Change in the cognitive function in RHI patients due to GGC supplementation.

Conditions Studied

Interventions

  • DRUG Gamma-glutamylcysteine (GGC)

Study Locations (1)

Pennsylvania

  • UPMC Presbyterian Hospital - Pittsburgh

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2026-03-20
Est. Completion 2027-12-27
Phase Phase 1

Sponsor

Pravat Mandal

3 total trials

What the Registry Record Tells You About NCT07050173

The ClinicalTrials.gov registry entry for NCT07050173 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Pravat Mandal, which has 3 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Repetitive Head Impacts appearing as the primary indexed condition, and to 1 intervention - of which Gamma-glutamylcysteine (GGC) is the first listed.

NCT07050173 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT07050173 about?

NCT07050173 is a clinical study titled "Monitoring Patients With Repetitive Head Impact With Gamma-glutamylcysteine Supplementation". The goal of this clinical trial is to test whether the gamma - glutamylcystiene (GGC) oral supplement can reach the brain and subsequently increase antioxidant glutathione (GSH) level in people with repetitive head impact (RHI). This will reduce the oxidative stress related injury in people with RHI...

What is the current status of trial NCT07050173?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2026-03-20. Estimated completion is 2027-12-27.

What conditions does trial NCT07050173 study?

This clinical trial studies the following conditions: Repetitive Head Impacts.

What interventions are being tested in trial NCT07050173?

The interventions under investigation include: Gamma-glutamylcysteine (GGC) (DRUG).

Who is sponsoring clinical trial NCT07050173?

This trial is sponsored by Pravat Mandal, which has 3 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07050173 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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