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RECRUITING NA

Physician Response Evaluation With Contextual Insights vs. Standard Engines - Artificial Intelligence RAG vs LLM Clinical Decision Support

NCT07037940 · View on ClinicalTrials.gov ↗

Study Summary

Clinical decision support tools powered by artificial intelligence are being rapidly integrated into medical practice. Two leading systems currently available to clinicians are OpenEvidence, which uses retrieval-augmented generation to access medical literature, and GPT-4, a large language model. While both tools show promise, their relative effectiveness in supporting clinical decision-making has not been directly compared. This study aims to evaluate how these tools influence diagnostic reasoning and management decisions among internal medicine physicians.

Conditions Studied

Interventions

  • OTHER OpenEvidence
  • OTHER GPT-4

Study Locations (2)

Massachusetts

  • Harvard Beth Israel Deaconess Medical Center — Boston

New York

  • MontefioreMC — The Bronx

Trial Details

FieldValue
Enrollment Target 26 participants
Start Date 2025-07-03
Est. Completion 2026-02
Phase NA

Sponsor

Montefiore Medical Center

280 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07037940

The ClinicalTrials.gov registry entry for NCT07037940 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 26 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Montefiore Medical Center, which has 280 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Large Language Models appearing as the primary indexed condition, and to 2 interventions — of which OpenEvidence is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07037940 reports 2 study locations spanning 2 distinct geographic areas — top geographies include Massachusetts, New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07037940 about?

NCT07037940 is a clinical study titled "Physician Response Evaluation With Contextual Insights vs. Standard Engines - Artificial Intelligence RAG vs LLM Clinical Decision Support". Clinical decision support tools powered by artificial intelligence are being rapidly integrated into medical practice. Two leading systems currently available to clinicians are OpenEvidence, which uses retrieval-augmented generation to access medical literature, and GPT-4, a large language model. Wh...

What is the current status of trial NCT07037940?

This trial is currently recruiting. It is a NA study. The enrollment target is 26 participants. The study started on 2025-07-03. Estimated completion is 2026-02.

What conditions does trial NCT07037940 study?

This clinical trial studies the following conditions: Large Language Models. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07037940?

The interventions under investigation include: OpenEvidence (OTHER), GPT-4 (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07037940?

This trial is sponsored by Montefiore Medical Center, which has 280 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07037940 being conducted?

This trial has 2 study locations across Massachusetts, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial