Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT07020026 · ClinicalTrials.gov registry record · Phase 2

Evaluation of Tau-Pathology in Sporadic and LRRK2 Parkinson's Disease

A Phase 2 study of Parkinson's Disease, sponsored by Michael J. Fox Foundation for Parkinson's Research.

Recruiting
Registry status
Phase 2
Development phase
60
Enrollment target
1
Study location

NCT07020026: Recruiting Phase 2 study of Parkinson's Disease, sponsored by Michael J. Fox Foundation for Parkinson's Research.

NCT07020026 is a Phase 2 study of Parkinson's Disease that is actively recruiting participants, run by Michael J. Fox Foundation for Parkinson's Research. The registered enrollment target is 60 participants, below the 635-participant average among 158 other Parkinson's Disease trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT07020026, a Phase 2 study of Parkinson's Disease, is actively recruiting participants, sponsored by Michael J. Fox Foundation for Parkinson's Research.

RECRUITING
Registry status
Phase 2
Development phase
60 participants
Enrollment target
1
Study location

Study Summary

The study aims to evaluate the burden of tau pathology in people with Sporadic and LRRK2 PD via in vivo imaging using the tau tracer, \[18F\]PI-2620, and a high resolution PET camera, NeuroEXPLORER.

Primary Outcome

Determination of \[18F\]PI-2620 binding in brain regions in all participants with NX acquired images to compare tau binding between study cohorts.

Conditions Studied

Interventions

  • DRUG [18F]PI-2620

Study Locations (1)

Connecticut

  • Institute for Neurodegenerative Disorders / XingImaging, LLC - New Haven

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2025-05-12
Est. Completion 2027-06
Phase Phase 2

What NCT07020026 shows while recruiting

NCT07020026 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 635-participant average among 158 other Parkinson's Disease trials with a reported enrollment target (91% lower).

The record links to 1 condition, with Parkinson's Disease appearing as the primary indexed condition, and to 1 intervention - of which [18F]PI-2620 is the first listed.

NCT07020026 reports a single indexed study location in Connecticut.

Frequently Asked Questions

What is clinical trial NCT07020026 about?

NCT07020026 is a clinical study titled "Evaluation of Tau-Pathology in Sporadic and LRRK2 Parkinson's Disease". The study aims to evaluate the burden of tau pathology in people with Sporadic and LRRK2 PD via in vivo imaging using the tau tracer, \[18F\]PI-2620, and a high resolution PET camera, NeuroEXPLORER.

What is the current status of trial NCT07020026?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2025-05-12. Estimated completion is 2027-06.

What conditions does trial NCT07020026 study?

This clinical trial studies the following conditions: Parkinson's Disease.

What interventions are being tested in trial NCT07020026?

The interventions under investigation include: [18F]PI-2620 (DRUG).

Who is sponsoring clinical trial NCT07020026?

This trial is sponsored by Michael J. Fox Foundation for Parkinson's Research, which has 14 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07020026 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Parkinson's Disease

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT07020026's enrollment target sits among peer trials

60 76th of 158 higher than 82 of 158 other Parkinson's Disease trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Parkinson's Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00576069 · 60 participants

    Mechanism(s)of Airflow Limitation in Moderate-severe Persistent Asthma

  • NCT01297400 · 60 participants · Phase 2

    Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns

  • NCT01734122 · 60 participants

    Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor

  • NCT01804634 · 60 participants · Phase 2

    Reduced Intensity Haploidentical BMT for High Risk Solid Tumors

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT07020026, the US trial registry maintained by the National Library of Medicine. NCT07020026 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.