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NCT07010666 · ClinicalTrials.gov registry record · NA

BHB and Cognition During Exercise-Heat Stress

A NA study, sponsored by University of South Carolina.

Completed
Registry status
NA
Development phase
18
Enrollment target

NCT07010666: Completed NA study, sponsored by University of South Carolina.

NCT07010666 is a NA study that has completed, run by University of South Carolina. The registered enrollment target is 18 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07010666, a NA study, has completed, sponsored by University of South Carolina.

COMPLETED
Registry status
NA
Development phase
18 participants
Enrollment target

Study Summary

The study investigates how consuming a ketone ester (BHB) along with caffeine impacts cognitive performance under heat stress, similar to what military personnel experience in hot environments. The extreme heat can impair brain function, affecting decision-making and performance, which is critical for Special Operations Forces (SOF). BHB provides an alternative energy source for the brain, potentially improving brain blood flow and cognition, particularly during "stressful" situations. By comparing ketone and carbohydrate intake with caffeine, this study aims to find better ways to maintain mental sharpness during stressful conditions. The results could help enhance the safety and effectiveness of military operations.

Primary Outcome

To determine if the intervention has an impact on inhibitory control by measuring reaction time to Go targets (hits).

Interventions

  • DIETARY_SUPPLEMENT Caffeine
  • DIETARY_SUPPLEMENT Carbohydrate
  • DIETARY_SUPPLEMENT Beta-Hydroxybutyrate

Trial Details

FieldValue
Enrollment Target 18 participants
Start Date 2025-01-29
Est. Completion 2025-05-12
Phase NA
University of South Carolina

157 total trials

What the finished NCT07010666 record still lists

NCT07010666 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 3 interventions - of which Caffeine is the first listed.

NCT07010666 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07010666 about?

NCT07010666 is a clinical study titled "BHB and Cognition During Exercise-Heat Stress". The study investigates how consuming a ketone ester (BHB) along with caffeine impacts cognitive performance under heat stress, similar to what military personnel experience in hot environments. The extreme heat can impair brain function, affecting decision-making and performance, which is critical f...

What is the current status of trial NCT07010666?

This trial is currently completed. It is a NA study. The enrollment target is 18 participants. The study started on 2025-01-29. Estimated completion is 2025-05-12.

What interventions are being tested in trial NCT07010666?

The interventions under investigation include: Caffeine (DIETARY_SUPPLEMENT), Carbohydrate (DIETARY_SUPPLEMENT), Beta-Hydroxybutyrate (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT07010666?

This trial is sponsored by University of South Carolina, which has 157 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07010666's enrollment target sits among peer trials

18 1863rd of 2000 higher than 130 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07010666, the US trial registry maintained by the National Library of Medicine. NCT07010666 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.