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NCT07005050 · ClinicalTrials.gov registry record · NA
Renal Pelvic Denervation Pilot Trial
A NA study of Uncontrolled Hypertension, sponsored by Verve Medical.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 5
- Study locations
NCT07005050: Recruiting NA study of Uncontrolled Hypertension, sponsored by Verve Medical.
NCT07005050 is a NA study of Uncontrolled Hypertension that is actively recruiting participants, run by Verve Medical. The registered enrollment target is 60 participants, below the 758-participant average among 10 other Uncontrolled Hypertension trials with a reported enrollment target (92% lower). The trial reports 5 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07005050, a NA study of Uncontrolled Hypertension, is actively recruiting participants, sponsored by Verve Medical.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 5
- Study locations
Study Summary
The RPD Pilot trial will evaluate the safety and effectiveness of Verve Medical's RPDTM renal denervation system for hypertensive patients with uncontrolled blood pressure despite use of two medications at a therapeutic dose. The novelty of the RPDTM system relates to its placement via natural orifice into the renal pelvis (bilaterally) for delivery of radiofrequency energy to ablate the nerves that pass through the outer wall of the renal pelvis, a technique referred to as renal pelvic denervation (RPD).
Primary Outcome
effects of the device/procedure on 24-hour blood pressure control in addition to use of 2 antihypertensive medications
Conditions Studied
Interventions
- DEVICE RPD
- DRUG Active hypertension medical therapy
Study Locations (5)
Minnesota
- University of Minnesota - Minneapolis
- Mayo Clinic - Rochester
Alabama
- University of Alabama at Birmingham - Birmingham
Arizona
- Panoramic Health / Southwest Kidney Institute, PLC - Surprise
Nevada
- DaVita Clinical Research - Las Vegas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2025-12-30 |
| Est. Completion | 2029-03-02 |
| Phase | NA |
What NCT07005050 shows while recruiting
NCT07005050 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 758-participant average among 10 other Uncontrolled Hypertension trials with a reported enrollment target (92% lower).
The record links to 1 condition, with Uncontrolled Hypertension appearing as the primary indexed condition, and to 2 interventions - of which RPD is the first listed.
NCT07005050 lists 5 locations in 4 states (Minnesota, Alabama, Arizona).
Frequently Asked Questions
What is clinical trial NCT07005050 about?
NCT07005050 is a clinical study titled "Renal Pelvic Denervation Pilot Trial". The RPD Pilot trial will evaluate the safety and effectiveness of Verve Medical's RPDTM renal denervation system for hypertensive patients with uncontrolled blood pressure despite use of two medications at a therapeutic dose. The novelty of the RPDTM system relates to its placement via natural orif...
What is the current status of trial NCT07005050?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2025-12-30. Estimated completion is 2029-03-02.
What conditions does trial NCT07005050 study?
This clinical trial studies the following conditions: Uncontrolled Hypertension.
What interventions are being tested in trial NCT07005050?
The interventions under investigation include: RPD (DEVICE), Active hypertension medical therapy (DRUG).
Who is sponsoring clinical trial NCT07005050?
This trial is sponsored by Verve Medical, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07005050 being conducted?
This trial has 5 study locations across Alabama, Arizona, Minnesota, Nevada. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07005050's enrollment target sits among peer trials
60 10th of 10 higher than 1 of 10 other Uncontrolled Hypertension trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Uncontrolled Hypertension trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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