Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07002450 · ClinicalTrials.gov registry record · NA
Left Atrial Imaging Prior to Cardioversion: Leveraging Computed Tomography to Rule Out Thrombus in The Emergency Department (LA CLOTTED)
A NA study, sponsored by Ottawa Heart Institute Research Corporation.
- Recruiting
- Registry status
- NA
- Development phase
- 190
- Enrollment target
NCT07002450: Recruiting NA study, sponsored by Ottawa Heart Institute Research Corporation.
NCT07002450 is a NA study that is actively recruiting participants, run by Ottawa Heart Institute Research Corporation. The registered enrollment target is 190 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (86% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07002450, a NA study, is actively recruiting participants, sponsored by Ottawa Heart Institute Research Corporation.
- RECRUITING
- Registry status
- NA
- Development phase
- 190 participants
- Enrollment target
Study Summary
The goal of this randomized clinical trial is to learn whether patients with symptomatic atrial fibrillation or atrial flutter (AF) who require heart imaging to rule out a blood clot before cardioversion would benefit from cardiac computed tomography angiography (CCT) in the emergency department (ED) compared to current standard of care management. This will be a multicenter trial evaluating whether CCT-facilitated cardioversion in the ED reduces hospital admission, reduces repeat presentations to hospital and improves patient quality of life compared to the current standard of care. Participants will undergo CCT-facilitated cardioversion or be treated according to current standard of care while in the ED and complete quality of life questionnaires in the ED and follow-up at 30 days.
Primary Outcome
Using a hierarchical win ratio: 1. All-cause death 2. Stroke, transient ischemic attack, or systemic embolism 3. Admission to hospital for a cardiac or AF related reason 4. Repeat presentation to hospital for a cardiac or AF related reason 5. Improvement in AF Effect On Quality-Of-Life Questionnaire (AFEQT) quality of life greater than or equal to 5 points
Interventions
- OTHER Standard of care management
- DIAGNOSTIC_TEST Cardiac computed tomography angiography
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 190 participants |
| Start Date | 2025-06-15 |
| Est. Completion | 2028-06-15 |
| Phase | NA |
What NCT07002450 shows while recruiting
NCT07002450 is an interventional study that assigns participants to a tested intervention. The registered 190 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (86% lower).
The record links to 0 conditions, and to 2 interventions - of which Standard of care management is the first listed.
NCT07002450 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07002450 about?
NCT07002450 is a clinical study titled "Left Atrial Imaging Prior to Cardioversion: Leveraging Computed Tomography to Rule Out Thrombus in The Emergency Department (LA CLOTTED)". The goal of this randomized clinical trial is to learn whether patients with symptomatic atrial fibrillation or atrial flutter (AF) who require heart imaging to rule out a blood clot before cardioversion would benefit from cardiac computed tomography angiography (CCT) in the emergency department (ED...
What is the current status of trial NCT07002450?
This trial is currently recruiting. It is a NA study. The enrollment target is 190 participants. The study started on 2025-06-15. Estimated completion is 2028-06-15.
What interventions are being tested in trial NCT07002450?
The interventions under investigation include: Standard of care management (OTHER), Cardiac computed tomography angiography (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT07002450?
This trial is sponsored by Ottawa Heart Institute Research Corporation, which has 10 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07002450's enrollment target sits among peer trials
190 574th of 2000 higher than 1,425 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT03257033 · 190 participants · Phase 3
Intra-arterial Gemcitabine vs. IV Gemcitabine and Nab-Paclitaxel Following Radiotherapy for LAPC
- NCT03642028 · 190 participants · Phase 4
Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress
- NCT04015609 · 190 participants · NA
Psychotherapy Intervention for Latinos With Advanced Cancer
- NCT04284397 · 190 participants · Early Phase 1
Identification of Critical Thermal Environments for Aged Adults
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI